Literature DB >> 30042049

Secondary hypertension due to a juxtaglomerular cell tumor.

Igor Nunes1, Tiago Santos2, Joana Tavares3, Lurdes Correia3, João Coutinho4, J M Braz Nogueira2, Leonor Carvalho2, J L Ducla Soares2.   

Abstract

Juxtaglomerular cell tumors are rare, generally benign, and they are one of the secondary surgically treatable causes of arterial hypertension. There are about 100 reported cases on literature, and the diagnosis is usually carried out based on a high clinic suspicion index, mostly in patients with hypokalemia and arterial hypertension. The diagnosis involves blood tests and imaging studies, but it is only definite with histopathological exam after surgical treatment. We present a case of a 22-year-old woman with resistant arterial hypertension and renal and cardiovascular target-organ lesions. High plasmatic renin and a nodular renal mass on magnetic resonance imaging were present. A tumorectomy was performed and the histological exam confirmed a reninoma. After surgery, blood pressure and serum renin values returned to normal without medication. This work focuses on the need to exclude rare secondary causes of hypertension in young patients with resistant forms of this disease.
Copyright © 2018 American Heart Association. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Hypertension; juxtaglomerular cell tumor; plasma renin activity; renin-secreting tumor

Year:  2018        PMID: 30042049     DOI: 10.1016/j.jash.2018.05.005

Source DB:  PubMed          Journal:  J Am Soc Hypertens        ISSN: 1878-7436


  3 in total

1.  Spindle Cell Hemangioma and Atypically Localized Juxtaglomerular Cell Tumor in a Patient with Hereditary BRIP1 Mutation: A Case Report.

Authors:  Jan Papez; Jiri Starha; Pavel Zerhau; Denisa Pavlovska; Marta Jezova; Tomas Jurencak; Katerina Slaba; Martin Sterba; Arpad Kerekes; Tomas Merta; Terezia Haluskova; Hana Palova; Ondrej Slaby; Jaroslav Sterba; Petr Jabandziev
Journal:  Genes (Basel)       Date:  2021-02-03       Impact factor: 4.096

2.  A case of atypical reninoma with mild hypertension and normal plasma renin activity but elevated plasma renin concentration.

Authors:  Baoping Wang; Li Ding; Shuanghua Xu; Yuxin Fan; Jiabo Wang; Xin Zhao; Diansheng Fu; Bo Bian; Kunlong Tang; Chunsheng Ni; Zuoliang Dong; Qing He; Ming Liu
Journal:  BMC Endocr Disord       Date:  2022-03-18       Impact factor: 2.763

3.  Juxtaglomerular cell tumor in a young male presenting with new onset congestive heart failure.

Authors:  Arvind Krishnan; Jeffy Jacob; Trushar Patel
Journal:  Urol Case Rep       Date:  2020-04-05
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.