Literature DB >> 30041550

Relationship between the FRAX index and physical and cognitive functioning in older people.

Yolanda González Silva1, Laura Abad Manteca2, Henar de la Red Gallego3, Mónica Álvarez Muñoz4, MaríaLuisa Rodríguez Carbajo5, Teresa Murcia Casado6, Lourdes Ausín Pérez7, Jésica Abadía Otero2, José-Luis Pérez-Castrillón2.   

Abstract

OBJECTIVE: To assess the relationship between the FRAX index and the Barthel index/MiniMental State Examination in older people. PATIENTS AND METHODS: Observational descriptive study. Demographic data, comorbidity, dependency and cognitive state, and risk of osteoporotic fracture were collected.
RESULTS: A total of 375 patients were included (60% female) Patients with a low-risk FRAX for hip fractures had a higher Mini-mental (25, 95% CI = 24-27 vs. 22, 95% = 21 to 23, p = .0001), a higher Barthel index (88, 95% CI = 84-93 vs 72, 69 to 76, p = .0001) without differences in the Charlson index. Bivariate analysis showed an inverse association between FRAX and scales but logistic regression showed only female sex (OR 4.4, 95% CI = 2.6-7.6) and the non-dependent Barthel index (OR = 0.104, 95% CI = 0.014-0.792) remained significant and. Barthel index/Mini-mental constructed a significant model capable of predicting a risk of hip fracture of >3% measured by the FRAX index, with an area under the curve of 0.76 (95% CI = 0.7-0.81).
CONCLUSIONS: The FRAX index is related to other markers of geriatric assessment and the association between these variables can predict a risk of hip fracture of >3% measured by the FRAX index. Key messages Geriatric assessment indexes may be as important as the FRAX index, which is based on clinical risk factors, in predicting the fracture risk in older patient.

Entities:  

Keywords:  Barthel Index; Charlson Index; FRAX; Mini-Mental State Examination; hip fracture

Mesh:

Year:  2018        PMID: 30041550     DOI: 10.1080/07853890.2018.1505052

Source DB:  PubMed          Journal:  Ann Med        ISSN: 0785-3890            Impact factor:   4.709


  2 in total

1.  Quality of Life in osteoporotic patients.

Authors:  Maria Rizzo; Gisella Tammaro; Amedeo Guarino; Morena Basso; Andrea Cozzolino; Massimo Mariconda
Journal:  Orthop Rev (Pavia)       Date:  2022-10-13

2.  Effect of nursing mode under the seamless connection between operating room and ward on severe traumatic brain injury patients in coma.

Authors:  Lanying Jiang; Qian Fei; Wei Song; Yali Jiang; Jianfen Pan; Guoqin Song
Journal:  Am J Transl Res       Date:  2021-05-15       Impact factor: 4.060

  2 in total

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