| Literature DB >> 30039916 |
Guilherme Silva de Mendonça1, Denis Fabiano de Souza1, Ana Cláudia de Alvarenga Cunha Brunelli1, Cristina Ila de Oliveira Peres1, Ercilhana Gonçalves Batista Freitas1, Gabriela Nolasco Lacerda1, Michelle Caixeta Dorneles1, Aldo José Peixoto2, Sebastião Rodrigues Ferreira-Filho1.
Abstract
Data on arterial stiffness in older populations, according to blood pressure (BP) levels, are scarce in Brazil. The objective of this study was to establish reference values for core measures of arterial stiffness, including carotid-femoral pulse wave velocity (cf-PWV) and aortic augmentation index (AIx), in a cohort of older individuals with normotension (NT) and hypertension. Cross-sectional analysis was performed with applanation tonometry data from 1192 patients aged 60 years or older. The authors classified patients according to their BP levels as having NT, controlled hypertension (CH), and uncontrolled hypertension (UH). The cf-PWV values were 9.11 ± 0.16 m/s (NT), 9.12 ± 0.18 m/s (CH), and 9.42 ± 2.2 m/s (UH) (P < 0.005; UH vs NT and CH). The AIx was 33.3% for the entire cohort and similar across all groups. The cf-PWV increased with age but reached a ceiling at 75 years. Compared with men, women had a higher AIx but similar cf-PWV levels. In conclusion, the markers of arterial stiffness were similar among individuals with NT/CH and higher among individuals with UH. ©2018 Wiley Periodicals, Inc.Entities:
Keywords: arterial stiffness; hypertension in the elderly; pulse wave velocity
Mesh:
Year: 2018 PMID: 30039916 PMCID: PMC8031136 DOI: 10.1111/jch.13358
Source DB: PubMed Journal: J Clin Hypertens (Greenwich) ISSN: 1524-6175 Impact factor: 3.738