Literature DB >> 30039437

Study of Serum CD147 Level in Patients with Transient Ischemic Attack and CD147 Expression in Atherosclerotic Plaque.

Bin Xu1, Chan Wu2, Wenqing Wu3, Yanguo Tan2, Nannan Sun2, Jian Cui2, Siyu Lu2, Jing Wang4, Shan Cen5.   

Abstract

There is growing evidence that highlighted the potential effects of CD147 in atherosclerosis, but the potential implication of CD147 in diagnosis and treatment of transient ischemic attack (TIA) and acute cerebral infarction (ACI) is still unclear. In this work, we investigated the serum level of CD147 in patients with TIA and ACI, and CD147 expression in atherosclerotic plaque. The result showed significantly increasing serum level of CD147 in patients with TIA and ACI, and increasing amount of CD147 in vulnerable plaque compared with that in migrating plaque. The serum level of CD147 was correlation with risk of stroke after an episode of TIA. These results together suggest a potential involvement of CD147 in the development and progression of TIA and ACI and CD147 as a potential biomarker for stroke prediction.

Entities:  

Keywords:  Acute cerebral infarction; Atherosclerosis; CD147; Transient ischemic attack; Vulnerable plaque

Mesh：

Substances：

Year:  2018        PMID： 30039437     DOI： 10.1007/s12265-018-9817-x

Source DB:  PubMed          Journal:  J Cardiovasc Transl Res        ISSN： 1937-5387            Impact factor:   4.132


  26 in total

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Journal:  Am J Physiol Cell Physiol       Date:  2010-09-01       Impact factor: 4.249

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3.  Intracoronary upregulation of platelet extracellular matrix metalloproteinase inducer (CD147) in coronary disease.

Authors:  Andy Yong; Gabrielle Pennings; Clement Wong; Ashkan Javadzadegan; David Brieger; Harry Lowe; Miao Qi; Masud Behnia; Steven Krilis; Leonard Kritharides
Journal:  Int J Cardiol       Date:  2011-12-20       Impact factor: 4.164

4.  Upstream regulation of matrix metalloproteinase by EMMPRIN; extracellular matrix metalloproteinase inducer in advanced atherosclerotic plaque.

Authors:  Young Won Yoon; Hyuck Moon Kwon; Ki-Chul Hwang; Eui-Young Choi; Bum-kee Hong; Dongsoo Kim; Hyun-Seung Kim; Sang Ho Cho; Kyung Soon Song; Giuseppe Sangiorgi
Journal:  Atherosclerosis       Date:  2005-01-19       Impact factor: 5.162

5.  Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer.

Authors:  R DeCastro; Y Zhang; H Guo; H Kataoka; M K Gordon; B p Toole; G Biswas
Journal:  J Invest Dermatol       Date:  1996-06       Impact factor: 8.551

6.  Expression of CD147 on phorbol-12-myristate-13-acetate (PMA)-treated U937 cells differentiating into foam cells.

Authors:  H H Yue; N Leng; Z B Wu; H M Li; X Y Li; P Zhu
Journal:  Arch Biochem Biophys       Date:  2009-05-01       Impact factor: 4.013

7.  Unstable carotid plaques exhibit raised matrix metalloproteinase-8 activity.

Authors:  K J Molloy; M M Thompson; J L Jones; E C Schwalbe; P R F Bell; A R Naylor; I M Loftus
Journal:  Circulation       Date:  2004-06-28       Impact factor: 29.690

8.  Extracellular matrix metalloproteinase inducer regulates matrix metalloproteinase activity in cardiovascular cells: implications in acute myocardial infarction.

Authors:  Roland Schmidt; Andreas Bültmann; Martin Ungerer; Nader Joghetaei; Ozgür Bülbül; Sven Thieme; Triantafyllos Chavakis; Bryan P Toole; Meinrad Gawaz; Albert Schömig; Andreas E May
Journal:  Circulation       Date:  2006-02-06       Impact factor: 29.690

9.  Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.

Authors:  Z S Galis; G K Sukhova; M W Lark; P Libby
Journal:  J Clin Invest       Date:  1994-12       Impact factor: 14.808

10.  Targeting the chemotactic function of CD147 reduces collagen-induced arthritis.

Authors:  Jesse M Damsker; Ifeanyi Okwumabua; Tatiana Pushkarsky; Kamalpreet Arora; Michael I Bukrinsky; Stephanie L Constant
Journal:  Immunology       Date:  2008-06-14       Impact factor: 7.397
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  2 in total

1.  Effect of intermittent hyperoxia on stem cell mobilization and cytokine expression.

Authors:  Kent J MacLaughlin; Gregory P Barton; Rudolf K Braun; Marlowe W Eldridge
Journal:  Med Gas Res       Date:  2019 Jul-Sep

2.  Assessment of Carotid Plaque Stability Using Contrast-Enhanced Ultrasound and Its Correlation With the Expression of CD147 and MMP-9 in the Plaque.

Authors:  Shanshan Huang; Xinyin Wu; Linlin Zhang; Jianming Wu; Yi He; Manlin Lai; Jiaqi Xu; Zhenzhou Li
Journal:  Front Comput Neurosci       Date:  2021-12-01       Impact factor: 2.380
  2 in total

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