Literature DB >> 3003690

A new member of the plasma protease inhibitor gene family.

H Ragg.   

Abstract

A 2.1-kb cDNA clone representing a new member of the protease inhibitor family was isolated from a human liver cDNA library. The inhibitor, named human Leuserpin 2 (hLS2), comprises 480 amino acids and contains a leucine residue at its putative reactive center. HLS2 is about 25-28% homologous to three human members of the plasma protease inhibitor family: antithrombin III, alpha 1-antitrypsin and alpha 1-antichymotrypsin. A comparison with published partial amino acid sequences shows that hLS2 is closely related to the thrombin inhibitor heparin cofactor II.

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Year:  1986        PMID： 3003690      PMCID： PMC339484          DOI： 10.1093/nar/14.2.1073

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  51 in total

1.  Amino acid composition and N-terminal sequence of antithrombin BM.

Authors:  I Witt; C Kaiser; W J Schrenk; P Wunderwald
Journal:  Thromb Res       Date:  1983-12-01       Impact factor: 3.944

2.  Reverse transcriptase and its associated ribonuclease H: interplay of two enzyme activities controls the yield of single-stranded complementary deoxyribonucleic acid.

Authors:  S L Berger; D M Wallace; R S Puskas; W H Eschenfeldt
Journal:  Biochemistry       Date:  1983-05-10       Impact factor: 3.162

Review 3.  Human plasma proteinase inhibitors.

Authors:  J Travis; G S Salvesen
Journal:  Annu Rev Biochem       Date:  1983       Impact factor: 23.643

4.  Cloning and expression in Escherichia coli of full-length complementary DNA coding for human alpha 1-antitrypsin.

Authors:  A Bollen; A Herzog; A Cravador; P Hérion; P Chuchana; A Vander Straten; R Loriau; P Jacobs; A van Elsen
Journal:  DNA       Date:  1983

5.  Not more than 117 base pairs of 5'-flanking sequence are required for inducible expression of a human IFN-alpha gene.

Authors:  H Ragg; C Weissmann
Journal:  Nature       Date:  1983 Jun 2-8       Impact factor: 49.962

6.  Cloning and expression of the cDNA for human antithrombin III.

Authors:  S C Bock; K L Wion; G A Vehar; R M Lawn
Journal:  Nucleic Acids Res       Date:  1982-12-20       Impact factor: 16.971

7.  Angiotensinogen is related to the antitrypsin-antithrombin-ovalbumin family.

Authors:  R F Doolittle
Journal:  Science       Date:  1983-10-28       Impact factor: 47.728

8.  Sequence homology between human alpha 1-antichymotrypsin, alpha 1-antitrypsin, and antithrombin III.

Authors:  T Chandra; R Stackhouse; V J Kidd; K J Robson; S L Woo
Journal:  Biochemistry       Date:  1983-10-25       Impact factor: 3.162

9.  Trans-complementable copy-number mutants of plasmid ColE1.

Authors:  A J Twigg; D Sherratt
Journal:  Nature       Date:  1980-01-10       Impact factor: 49.962

10.  Mutation of antitrypsin to antithrombin. alpha 1-antitrypsin Pittsburgh (358 Met leads to Arg), a fatal bleeding disorder.

Authors:  M C Owen; S O Brennan; J H Lewis; R W Carrell
Journal:  N Engl J Med       Date:  1983-09-22       Impact factor: 176.079
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  6 in total

1.  Anti-thrombin activities of heparin. Effect of saccharide chain length on thrombin inhibition by heparin cofactor II and by antithrombin.

Authors:  B Bray; D A Lane; J M Freyssinet; G Pejler; U Lindahl
Journal:  Biochem J       Date:  1989-08-15       Impact factor: 3.857

2.  Glycosaminoglycan-binding properties and kinetic characterization of human heparin cofactor II expressed in Escherichia coli.

Authors:  Suryakala Sarilla; Sally Y Habib; Douglas M Tollefsen; David B Friedman; Diana R Arnett; Ingrid M Verhamme
Journal:  Anal Biochem       Date:  2010-07-27       Impact factor: 3.365

Review 3.  Glycosaminoglycans and the regulation of blood coagulation.

Authors:  M C Bourin; U Lindahl
Journal:  Biochem J       Date:  1993-01-15       Impact factor: 3.857

4.  Type II hereditary angioneurotic edema that may result from a single nucleotide change in the codon for alanine-436 in the C1 inhibitor gene.

Authors:  N J Levy; N Ramesh; M Cicardi; R A Harrison; A E Davis
Journal:  Proc Natl Acad Sci U S A       Date:  1990-01       Impact factor: 11.205

5.  Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation.

Authors:  K Suzuki; H Kusumoto; Y Deyashiki; J Nishioka; I Maruyama; M Zushi; S Kawahara; G Honda; S Yamamoto; S Horiguchi
Journal:  EMBO J       Date:  1987-07       Impact factor: 11.598

6.  The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand.

Authors:  Amanda J Boyle; Leigh Ann Roddick; Varsha Bhakta; Melissa D Lambourne; Murray S Junop; Patricia C Liaw; Jeffrey I Weitz; William P Sheffield
Journal:  BMC Biochem       Date:  2013-03-07       Impact factor: 4.059
  6 in total

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