Literature DB >> 30036877

Eribulin as a Feasible and Safe Monotherapy in a Dialytic Pretreated Woman with Metastatic Breast Cancer: A Case Report.

Raffaele Nettuno, Carmine Menditto.   

Abstract

Eribulin, a non-taxane inhibitor of microtubule dynamics, is approved for the treatment of metastatic breast cancer patients after progression with anthracyclines and taxanes. Nevertheless, to our knowledge, information on its use in dialytic patients is not available to date. This report describes the case of a chemo-pretreated dialytic woman with lung, bone, and liver metastasis from breast cancer, who experienced stable disease with a response < 20% with eribulin in fifth line after 3 hormonal lines and 1 chemotherapy line. This case suggests the feasibility and good tolerability of eribulin in this peculiar setting.
© 2018 S. Karger AG, Basel.

Entities:  

Keywords:  Chemotherapy; Dialysis; Eribulin; Metastatic breast cancer; Taxanes

Mesh:

Substances:

Year:  2018        PMID: 30036877      PMCID: PMC6193746          DOI: 10.1159/000489064

Source DB:  PubMed          Journal:  Oncology        ISSN: 0030-2414            Impact factor:   2.935


  11 in total

Review 1.  Eribulin -- a review of preclinical and clinical studies.

Authors:  Umang Swami; Imran Chaudhary; Mohammad H Ghalib; Sanjay Goel
Journal:  Crit Rev Oncol Hematol       Date:  2011-04-14       Impact factor: 6.312

Review 2.  Eribulin mesylate.

Authors:  Sarika Jain; Linda T Vahdat
Journal:  Clin Cancer Res       Date:  2011-08-22       Impact factor: 12.531

Review 3.  Cancer management in patients with end-stage renal disease.

Authors:  Jonathan D Eneman; George K Philips
Journal:  Oncology (Williston Park)       Date:  2005-08       Impact factor: 2.990

4.  Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): a phase 3 open-label randomised study.

Authors:  Javier Cortes; Joyce O'Shaughnessy; David Loesch; Joanne L Blum; Linda T Vahdat; Katarina Petrakova; Philippe Chollet; Alexey Manikas; Veronique Diéras; Thierry Delozier; Vladimir Vladimirov; Fatima Cardoso; Han Koh; Philippe Bougnoux; Corina E Dutcus; Seth Seegobin; Denis Mir; Nicole Meneses; Jantien Wanders; Chris Twelves
Journal:  Lancet       Date:  2011-03-02       Impact factor: 79.321

5.  The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth.

Authors:  Mary Ann Jordan; Kathryn Kamath; Tapas Manna; Tatiana Okouneva; Herbert P Miller; Celia Davis; Bruce A Littlefield; Leslie Wilson
Journal:  Mol Cancer Ther       Date:  2005-07       Impact factor: 6.261

6.  Induction of morphological and biochemical apoptosis following prolonged mitotic blockage by halichondrin B macrocyclic ketone analog E7389.

Authors:  Galina Kuznetsov; Murray J Towle; Hongsheng Cheng; Takanori Kawamura; Karen TenDyke; Diana Liu; Yoshito Kishi; Melvin J Yu; Bruce A Littlefield
Journal:  Cancer Res       Date:  2004-08-15       Impact factor: 12.701

7.  Safety and efficacy of pembrolizumab in a patient with advanced melanoma on haemodialysis.

Authors:  Rubens Chang; Keisuke Shirai
Journal:  BMJ Case Rep       Date:  2016-09-22

8.  Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase.

Authors:  Tatiana Okouneva; Olga Azarenko; Leslie Wilson; Bruce A Littlefield; Mary Ann Jordan
Journal:  Mol Cancer Ther       Date:  2008-07       Impact factor: 6.261

9.  Eribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instability.

Authors:  Jennifer A Smith; Leslie Wilson; Olga Azarenko; Xiaojie Zhu; Bryan M Lewis; Bruce A Littlefield; Mary Ann Jordan
Journal:  Biochemistry       Date:  2010-02-16       Impact factor: 3.162

10.  Safety of Regular-Dose Imatinib Therapy in Patients with Gastrointestinal Stromal Tumors Undergoing Dialysis.

Authors:  Ryota Niikura; Takako Serizawa; Atsuo Yamada; Shuntaro Yoshida; Mariko Tanaka; Yoshihiro Hirata; Kazuhiko Koike
Journal:  Case Rep Gastroenterol       Date:  2016-05-19
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