| Literature DB >> 30036617 |
Niyati Lobo1, Meghana Kulkarni1, Simon Hughes2, Rajesh Nair1, Muhammad Shamim Khan1, Ramesh Thurairaja3.
Abstract
Radiotherapy is widely used as a curative treatment for pelvic malignancies. The location of these organs leads to unavoidable exposure of the bladder, urethra, and distal ureters to radiation and may cause subsequent development of radiation cystitis, fistulae, strictures, and secondary malignancy. As cancer survival improves, an ever-increasing number of patients is living with the long-term complications of radiotherapy. Symptoms are not only debilitating for the patient but also pose a treatment challenge to the urologist. This review provides a comprehensive overview of the pathophysiology, clinical presentation, and current management strategies for the urologic complications following pelvic radiotherapy.Entities:
Mesh:
Year: 2018 PMID: 30036617 DOI: 10.1016/j.urology.2018.07.017
Source DB: PubMed Journal: Urology ISSN: 0090-4295 Impact factor: 2.649