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Literature DB >> 300359

Selective response of lymphocytes from Treponema pallidum-infected rabbits to mitogens and Treponema reiteri.

Abstract

The in vitro response of peripheral blood lymphocytes from rabbit infected with Treponema pallidum was examined using various mitogens and avirulent Treponema reiteri. For the first 4 weeks after treponemal infection, the response of lymphocytes from syphilitic rabbits to phytohemagglutinin and pokeweed mitogen was markedly reduced in comparison to uninfected controls. Lymphocytes from both groups of rabbits responded normally to class-specific immunoglobulin anti-sera (anti-immunoglobulin M and anti-immunoglobulin G) and T. reiteri.

Entities: Disease Species

Mesh：

Substances：

Year: 1977 PMID： 300359 PMCID： PMC421384 DOI： 10.1128/iai.15.2.417-422.1977

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

24 in total

1. Attempt to protect rabbits against experimental syphilis by passive immunization.

Authors: M Sepetjian; D Salussola; J Thivolet
Journal: Br J Vener Dis Date: 1973-08

2. Effects of passive immunization on experimental syphilis in the rabbit.

Authors: T B Turner; P H Hardy; B Newman; E E Nell
Journal: Johns Hopkins Med J Date: 1973-11

3. DNA synthesis by cultured lymphocytes: a modified method for measuring 3H-thymidine incorporation.

Authors: R M Williams
Journal: Cell Immunol Date: 1973-12 Impact factor: 4.868

4. The response of rabbit lymphocytes to mitogens and alloantigens: evidence for T cell heterogeneity.

Authors: H Ozer; B H Waksman
Journal: J Immunol Date: 1974-12 Impact factor: 5.422

5. The relationship between lymphocyte transformation and immune responses. II. Correlations between transformation and humoral and cellular immune responses.

Authors: D Benezra; I Gery; A M Davies
Journal: Clin Exp Immunol Date: 1969-07 Impact factor: 4.330

4. Uneven distribution of antitreponema antibody acitivity in differing immunoglobulin G fractions from patients with early syphilis.

Authors: J J van der Sluis; M Boer
Journal: Infect Immun Date: 1980-09 Impact factor: 3.441

5. Transfer of resistance with syphilitic immune cells: lack of correlation with mitogenic activity.

Authors: R F Schell; J L LeFrock; J K Chan
Journal: Infect Immun Date: 1982-01 Impact factor: 3.441

6. Alterations in T lymphocytes and T-lymphocyte subpopulations in patients with syphilis.

Authors: J R Jensen; E From
Journal: Br J Vener Dis Date: 1982-02

7. Detection of circulating immune complexes in the sera of rabbits with experimental syphilis: possible role in immunoregulation.

Authors: R E Baughn; K S Tung; D M Musher
Journal: Infect Immun Date: 1980-08 Impact factor: 3.441

Selective response of lymphocytes from Treponema pallidum-infected rabbits to mitogens and Treponema reiteri.

1. Attempt to protect rabbits against experimental syphilis by passive immunization.

2. Effects of passive immunization on experimental syphilis in the rabbit.

3. DNA synthesis by cultured lymphocytes: a modified method for measuring 3H-thymidine incorporation.

4. The response of rabbit lymphocytes to mitogens and alloantigens: evidence for T cell heterogeneity.

5. The relationship between lymphocyte transformation and immune responses. II. Correlations between transformation and humoral and cellular immune responses.

6. Reduced lymphocyte transformation due to a plasma factor in patients with active syphilis.

7. Relationship of in vitro lymphocyte transformation to delayed hypersensitivity in guinea pigs and man.

8. Lymphocyte transformation in syphilis: an in vitro correlate of immune suppression in vivo?

9. Suppressor cells in rabbit peripheral blood.

10. Detection of nonspecific resistance to Listeria monocytogenes in rabbits infected with Treponema pallidum.

1. Selective in vitro response of thymus-derived lymphocytes from Treponema pallidum-infected rabbits.

2. Ultrastructural study of satellite lymph nodes in syphilitic rabbits.

3. T lymphoid cells in primary syphilis. Quantitative studies.

4. Uneven distribution of antitreponema antibody acitivity in differing immunoglobulin G fractions from patients with early syphilis.

5. Transfer of resistance with syphilitic immune cells: lack of correlation with mitogenic activity.

6. Alterations in T lymphocytes and T-lymphocyte subpopulations in patients with syphilis.

7. Detection of circulating immune complexes in the sera of rabbits with experimental syphilis: possible role in immunoregulation.

8. Response of syphilitic rabbits to reinfection with homologous and heterologous Treponema pallidum strains.

9. Parasitism by virulent Treponema pallidum of host cell surfaces.

Review 10. Cell-mediated immunity during syphilis.