| Literature DB >> 3003538 |
Abstract
In E. coli K-12 the argF gene is flanked by ISI sequences in direct repeat. Mutants that overproduce the argF-coded enzyme ornithine transcarbamylase can be selected; we have shown that in one class of these mutants there is an approximately forty five-fold amplification of the region bounded by the ISI repeats. This class of mutants has been detected only in strains in which the F-factor is integrated in cis to the region.Entities:
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Year: 1985 PMID: 3003538 DOI: 10.1007/bf00425683
Source DB: PubMed Journal: Mol Gen Genet ISSN: 0026-8925