Literature DB >> 30034852

Clinical care for patients with recurrent myocardial ischemia in Germany-the VOICES trial.

Dominik Berliner1, Lars S Maier2, Ulrike Wollenberg3, Roger Limberg3, Jan D Schmitto4, Dirk Westermann5, Johann Bauersachs1.   

Abstract

BACKGROUND: Chronic ischemic heart disease is frequent and represents the most common cause of death in western countries. Angina pectoris, the clinical symptom of myocardial ischemia, is associated with increased morbidity and mortality also in patients without obstructive coronary artery disease. The aim of this study was to investigate the current care of patients with recurrent myocardial ischemia after ruling out significant coronary stenosis in the setting of outpatient care.
METHODS: Data were obtained by a detailed and structured survey. German cardiologists in outpatient care were interviewed about the management and treatment of outpatients with recurrent angina pectoris after ruling out significant stenoses by coronary angiography. Items were analysed using rating scales [1-10] by means of descriptive methods. Absolute and relative frequency distribution was calculated for the characterisation of qualitative data and multiple-choice questions.
RESULTS: The interviews of 731 cardiologic experts could be included in this analysis. The main results showed that history taking seems to be one major problem in those patients-more than 10% of the expert cardiologists admit that they do not perform a detailed history taking of patients with recurrent angina pectoris. While a classification of the symptoms by means of the CCS classification is rated as important such a classification is not used on a regular basis. Extra-cardiac causes are frequently not excluded before performing coronary angiography (>10% of the cases). A significant fraction (20%) of German cardiologists does not consider the initiation of a specific, antianginal medical treatment as their objective.
CONCLUSIONS: The trial revealed deficiencies in the history taking, the proper classification of the symptoms, and the initiation of an adequate drug therapy in patients with recurrent angina pectoris after exclusion of significant coronary stenoses.

Entities:  

Keywords:  Angina pectoris; endothelial dysfunction; myocardial ischemia; non-obstructive coronary artery disease; small vessel disease

Year:  2018        PMID: 30034852      PMCID: PMC6035955          DOI: 10.21037/jtd.2017.10.123

Source DB:  PubMed          Journal:  J Thorac Dis        ISSN: 2072-1439            Impact factor:   2.895


  19 in total

1.  2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology.

Authors:  Gilles Montalescot; Udo Sechtem; Stephan Achenbach; Felicita Andreotti; Chris Arden; Andrzej Budaj; Raffaele Bugiardini; Filippo Crea; Thomas Cuisset; Carlo Di Mario; J Rafael Ferreira; Bernard J Gersh; Anselm K Gitt; Jean-Sebastien Hulot; Nikolaus Marx; Lionel H Opie; Matthias Pfisterer; Eva Prescott; Frank Ruschitzka; Manel Sabaté; Roxy Senior; David Paul Taggart; Ernst E van der Wall; Christiaan J M Vrints; Jose Luis Zamorano; Stephan Achenbach; Helmut Baumgartner; Jeroen J Bax; Héctor Bueno; Veronica Dean; Christi Deaton; Cetin Erol; Robert Fagard; Roberto Ferrari; David Hasdai; Arno W Hoes; Paulus Kirchhof; Juhani Knuuti; Philippe Kolh; Patrizio Lancellotti; Ales Linhart; Petros Nihoyannopoulos; Massimo F Piepoli; Piotr Ponikowski; Per Anton Sirnes; Juan Luis Tamargo; Michal Tendera; Adam Torbicki; William Wijns; Stephan Windecker; Juhani Knuuti; Marco Valgimigli; Héctor Bueno; Marc J Claeys; Norbert Donner-Banzhoff; Cetin Erol; Herbert Frank; Christian Funck-Brentano; Oliver Gaemperli; José R Gonzalez-Juanatey; Michalis Hamilos; David Hasdai; Steen Husted; Stefan K James; Kari Kervinen; Philippe Kolh; Steen Dalby Kristensen; Patrizio Lancellotti; Aldo Pietro Maggioni; Massimo F Piepoli; Axel R Pries; Francesco Romeo; Lars Rydén; Maarten L Simoons; Per Anton Sirnes; Ph Gabriel Steg; Adam Timmis; William Wijns; Stephan Windecker; Aylin Yildirir; Jose Luis Zamorano
Journal:  Eur Heart J       Date:  2013-08-30       Impact factor: 29.983

2.  Microvascular dysfunction in the spectrum of coronary instability.

Authors:  Alberto Ranieri De Caterina; Leonarda Galiuto; Elisa Fedele; Filippo Crea
Journal:  Am J Cardiol       Date:  2011-08-24       Impact factor: 2.778

3.  Letter: Grading of angina pectoris.

Authors:  L Campeau
Journal:  Circulation       Date:  1976-09       Impact factor: 29.690

4.  Stable angina pectoris with no obstructive coronary artery disease is associated with increased risks of major adverse cardiovascular events.

Authors:  Lasse Jespersen; Anders Hvelplund; Steen Z Abildstrøm; Frants Pedersen; Søren Galatius; Jan K Madsen; Erik Jørgensen; Henning Kelbæk; Eva Prescott
Journal:  Eur Heart J       Date:  2011-09-11       Impact factor: 29.983

5.  Invasive evaluation of patients with angina in the absence of obstructive coronary artery disease.

Authors:  Bong-Ki Lee; Hong-Seok Lim; William F Fearon; Andy S Yong; Ryotaro Yamada; Shigemitsu Tanaka; David P Lee; Alan C Yeung; Jennifer A Tremmel
Journal:  Circulation       Date:  2015-02-20       Impact factor: 29.690

6.  High prevalence of a pathological response to acetylcholine testing in patients with stable angina pectoris and unobstructed coronary arteries. The ACOVA Study (Abnormal COronary VAsomotion in patients with stable angina and unobstructed coronary arteries).

Authors:  Peter Ong; Anastasios Athanasiadis; Gabor Borgulya; Heiko Mahrholdt; Juan Carlos Kaski; Udo Sechtem
Journal:  J Am Coll Cardiol       Date:  2012-02-14       Impact factor: 24.094

Review 7.  Role of endothelial dysfunction and insulin resistance in angina pectoris and normal coronary angiogram.

Authors:  Lucilla Domenica Monti; Pier Marco Piatti
Journal:  Herz       Date:  2005-02       Impact factor: 1.443

8.  Angina with "normal" coronary arteries: sex differences in outcomes.

Authors:  Karin H Humphries; Aihua Pu; Min Gao; Ronald G Carere; Louise Pilote
Journal:  Am Heart J       Date:  2007-12-19       Impact factor: 4.749

9.  Reduction of coronary reserve: a mechanism for angina pectoris in patients with arterial hypertension and normal coronary arteries.

Authors:  D Opherk; G Mall; H Zebe; F Schwarz; E Weihe; J Manthey; W Kübler
Journal:  Circulation       Date:  1984-01       Impact factor: 29.690

10.  Burden of hospital admission and repeat angiography in angina pectoris patients with and without coronary artery disease: a registry-based cohort study.

Authors:  Lasse Jespersen; Steen Z Abildstrom; Anders Hvelplund; Jan K Madsen; Soren Galatius; Frants Pedersen; Soren Hojberg; Eva Prescott
Journal:  PLoS One       Date:  2014-04-04       Impact factor: 3.240

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  2 in total

1.  PCSK9 Modulates Macrophage Polarization-Mediated Ventricular Remodeling after Myocardial Infarction.

Authors:  Feifei Wang; Min Li; Aidong Zhang; Hairui Li; Can Jiang; Jun Guo
Journal:  J Immunol Res       Date:  2022-07-04       Impact factor: 4.493

Review 2.  Post-percutaneous coronary intervention angina: From physiopathological mechanisms to individualized treatment.

Authors:  Leonardo De Luca; Giuseppe M C Rosano; Ilaria Spoletini
Journal:  Cardiol J       Date:  2021-04-12       Impact factor: 3.487

  2 in total

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