Literature DB >> 30031797

Molecular targeted therapy: Treating cancer with specificity.

Yeuan Ting Lee1, Yi Jer Tan1, Chern Ein Oon2.   

Abstract

Molecular targeted therapies are revolutionized therapeutics which interfere with specific molecules to block cancer growth, progression, and metastasis. Many molecular targeted therapies approved by the Food and Drug Administration (FDA), have demonstrated remarkable clinical success in the treatment of a myriad of cancer types including breast, leukemia, colorectal, lung, and ovarian cancers. This review provides an update on the different types of molecular targeted therapies used in the treatment of cancer, focusing on the fundamentals of molecular targeted therapy, its mode of action in cancer treatment, as well as its advantages and limitations.
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cancer; Gene therapy; Molecular targeted therapy; Monoclonal antibody; Small molecule; Therapeutic cancer vaccine

Mesh:

Substances:

Year:  2018        PMID: 30031797     DOI: 10.1016/j.ejphar.2018.07.034

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  184 in total

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