Literature DB >> 30030835

Notch and T Cell Function - A Complex Tale.

Jyothi Vijayaraghavan1, Barbara A Osborne2,3.   

Abstract

Notch drives critical decisions in a multitude of developmental decisions in many invertebrate and vertebrate organisms including flies, worms, fish, mice and humans. Therefore, it is not surprising that Notch family members also play a key role in cell fate choices in the vertebrate immune system. This review highlights the critical function of Notch in the development of mature T lymphocytes from hematopoietic precursors and describes the role of Notch in mature T cell activation, proliferation and differentiation.

Entities:  

Keywords:  CD4+; CD8+; Notch; T cell; Th1; Th17; Th2; Tregs

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Substances：

Year:  2018        PMID： 30030835     DOI： 10.1007/978-3-319-89512-3_17

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  7 in total

1.  GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells.

Authors:  Eric Perkey; Dave Maurice De Sousa; Léolène Carrington; Jooho Chung; Alexander Dils; David Granadier; Ute Koch; Freddy Radtke; Burkhard Ludewig; Bruce R Blazar; Christian W Siebel; Todd V Brennan; Jeffrey Nolz; Nathalie Labrecque; Ivan Maillard
Journal:  J Immunol       Date:  2020-02-14       Impact factor: 5.422

Review 2.  Targeting Notch in oncology: the path forward.

Authors:  Samarpan Majumder; Judy S Crabtree; Todd E Golde; Lisa M Minter; Barbara A Osborne; Lucio Miele
Journal:  Nat Rev Drug Discov       Date:  2020-12-08       Impact factor: 84.694

3.  Elevated Notch1 enhances interleukin-22 production by CD4+ T cells via aryl hydrocarbon receptor in patients with lung adenocarcinoma.

Authors:  Bo Pang; Cong Hu; Na Xing; Lei Xu; Songling Zhang; Xiaowei Yu
Journal:  Biosci Rep       Date:  2018-12-14       Impact factor: 3.840

Review 4.  Notch Signaling Regulates Immune Responses in Atherosclerosis.

Authors:  Francesco Vieceli Dalla Sega; Francesca Fortini; Giorgio Aquila; Gianluca Campo; Mauro Vaccarezza; Paola Rizzo
Journal:  Front Immunol       Date:  2019-05-22       Impact factor: 7.561

5.  CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells.

Authors:  Ankita Mitra; Sudarvili Shanthalingam; Heather L Sherman; Khushboo Singh; Mine Canakci; Joe A Torres; Rebecca Lawlor; Yong Ran; Todd E Golde; Lucio Miele; Sankaran Thayumanavan; Lisa M Minter; Barbara A Osborne
Journal:  Front Immunol       Date:  2020-05-07       Impact factor: 7.561

Review 6.  Complement Has Brains-Do Intracellular Complement and Immunometabolism Cooperate in Tissue Homeostasis and Behavior?

Authors:  Natalia Kunz; Claudia Kemper
Journal:  Front Immunol       Date:  2021-02-25       Impact factor: 7.561

Review 7.  Notch signaling in female cancers: a multifaceted node to overcome drug resistance.

Authors:  Maria V Giuli; Angelica Mancusi; Eugenia Giuliani; Isabella Screpanti; Saula Checquolo
Journal:  Cancer Drug Resist       Date:  2021-08-05
  7 in total

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