Literature DB >> 30030508

Rituximab primarily targets an intra-clonal BCR signaling proficient CLL subpopulation characterized by high CD20 levels.

Gabriela Pavlasova1,2, Marek Borsky2, Veronika Svobodova1,2, Jan Oppelt1, Katerina Cerna1,2, Jitka Novotna2, Vaclav Seda1,2, Miloslava Fojtova3, Jiri Fajkus3, Yvona Brychtova2, Michael Doubek2, Sarka Pospisilova2, Jiri Mayer2, Marek Mraz4,5.   

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Year:  2018        PMID： 30030508     DOI： 10.1038/s41375-018-0211-0

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  11 in total

1.  Idelalisib activates AKT via increased recruitment of PI3Kδ/PI3Kβ to BCR signalosome while reducing PDK1 in post-therapy CLL cells.

Authors:  Hasan Mahmud; Guru P Maiti; Murali K Mamidi; Mariana T Mendez; Stacey M Fernandes; Sara K Vesely; Jennifer Holter-Chakrabarty; Jennifer R Brown; Asish K Ghosh
Journal:  Leukemia       Date:  2022-05-14       Impact factor: 12.883

2.  The different predictive effects of the intensity and proportion of CD20 expression on the prognosis of B-lineage acute lymphocyte leukemia.

Authors:  Yun Tian; Xiaojiao Wang; Hao Ai; Xiaodong Lyu; Qian Wang; Xudong Wei; Yongping Song; Qingsong Yin
Journal:  EJHaem       Date:  2022-03-25

Review 3.  In Vitro and In Vivo Models of CLL-T Cell Interactions: Implications for Drug Testing.

Authors:  Eva Hoferkova; Sona Kadakova; Marek Mraz
Journal:  Cancers (Basel)       Date:  2022-06-23       Impact factor: 6.575

4.  FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia.

Authors:  Vaclav Seda; Eva Vojackova; Laura Ondrisova; Lenka Kostalova; Sonali Sharma; Tomas Loja; Gabriela Mladonicka Pavlasova; Daniel Zicha; Marie Kudlickova Peskova; Jan Krivanek; Kvetoslava Liskova; Leos Kren; Vladimir Benes; Katerina Musilova Litzmanova; Marek Borsky; Jan Oppelt; Jan Verner; Sarka Pospisilova; Yvona Brychtova; Anna Panovska; Zhi Tan; Shuxing Zhang; Michael Doubek; Katerina Amruz Cerna; Jiri Mayer; Marek Mraz
Journal:  Blood       Date:  2021-09-02       Impact factor: 22.113

5.  Identification of BLNK and BTK as mediators of rituximab-induced programmed cell death by CRISPR screens in GCB-subtype diffuse large B-cell lymphoma.

Authors:  Emil Aagaard Thomsen; Anne Bruun Rovsing; Mads Valdemar Anderson; Hanne Due; Jinrong Huang; Yonglun Luo; Karen Dybkaer; Jacob Giehm Mikkelsen
Journal:  Mol Oncol       Date:  2020-07-16       Impact factor: 6.603

6.  High CXCR3 on Leukemic Cells Distinguishes IgHV mut from IgHV unmut in Chronic Lymphocytic Leukemia: Evidence from CD5high and CD5low Clones.

Authors:  Gayane Manukyan; Tomas Papajik; Zuzana Mikulkova; Renata Urbanova; Veronika Smotkova Kraiczova; Jakub Savara; Milos Kudelka; Peter Turcsanyi; Eva Kriegova
Journal:  J Immunol Res       Date:  2020-06-20       Impact factor: 4.818

7.  Genetic and Non-Genetic Mechanisms of Resistance to BCR Signaling Inhibitors in B Cell Malignancies.

Authors:  Laura Ondrisova; Marek Mraz
Journal:  Front Oncol       Date:  2020-10-26       Impact factor: 6.244

8.  CD20 is dispensable for B-cell receptor signaling but is required for proper actin polymerization, adhesion and migration of malignant B cells.

Authors:  Veronika Kozlova; Aneta Ledererova; Adriana Ladungova; Helena Peschelova; Pavlina Janovska; Aleksander Slusarczyk; Joanna Domagala; Pavel Kopcil; Viera Vakulova; Jan Oppelt; Vitezslav Bryja; Michael Doubek; Jiri Mayer; Sarka Pospisilova; Michal Smida
Journal:  PLoS One       Date:  2020-03-25       Impact factor: 3.240

9.  miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors.

Authors:  Sonali Sharma; Gabriela Mladonicka Pavlasova; Vaclav Seda; Katerina Amruz Cerna; Eva Vojackova; Daniel Filip; Laura Ondrisova; Veronika Sandova; Lenka Kostalova; Pedro F Zeni; Marek Borsky; Jan Oppelt; Kvetoslava Liskova; Leos Kren; Andrea Janikova; Sarka Pospisilova; Stacey M Fernandes; Medhat Shehata; Laura Z Rassenti; Ulrich Jaeger; Michael Doubek; Matthew S Davids; Jennifer R Brown; Jiri Mayer; Thomas J Kipps; Marek Mraz
Journal:  Blood       Date:  2021-05-06       Impact factor: 22.113

Review 10.  The regulation and function of CD20: an "enigma" of B-cell biology and targeted therapy.

Authors:  Gabriela Pavlasova; Marek Mraz
Journal:  Haematologica       Date:  2020-06       Impact factor: 11.047
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