Literature DB >> 3002736

Effect of exogenous mouse interferon on murine fulminant hepatitis induced by mouse hepatitis virus type 2.

Y Kato, Y Noda, M Unoura, N Tanaka, K Kobayashi, N Hattori, K Hatano, S Kobayashi.   

Abstract

We investigated the effect of exogenous mouse alpha- + beta-interferon produced by mouse L cells on the growth of mouse hepatitis virus type 2 (MHV-2) in the liver, the development of liver cell necrosis, and survival in murine fulminant hepatitis induced by MHV-2. Murine fulminant hepatitis was induced in 4-week-old male ICR mice by intraperitoneal inoculation of MHV-2. Mouse interferon (10(3) IU/mouse/day) was intraperitoneally injected every day. Exogenous mouse interferon suppressed both the growth of MHV-2 in the liver tissue and development of liver cell necrosis, and prolonged the survival. It was also found that the earlier mouse interferon was administered, the greater was the prolongation of survival.

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Year:  1986        PMID： 3002736      PMCID： PMC7088026          DOI： 10.1007/bf01300705

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN： 0163-2116            Impact factor:   3.199


  12 in total

1.  A GENERALIZED WILCOXON TEST FOR COMPARING ARBITRARILY SINGLY-CENSORED SAMPLES.

Authors:  E A GEHAN
Journal:  Biometrika       Date:  1965-06       Impact factor: 2.445

2.  MOUSE MACROPHAGES AS HOST CELLS FOR THE MOUSE HEPATITIS VIRUS AND THE GENETIC BASIS OF THEIR SUSCEPTIBILITY.

Authors:  F B Bang; A Warwick
Journal:  Proc Natl Acad Sci U S A       Date:  1960-08       Impact factor: 11.205

3.  Interferon system in acute viral hepatitis.

Authors:  S Levin; T Hahn
Journal:  Lancet       Date:  1982-03-13       Impact factor: 79.321

4.  Activation of natural killer cells and induction of interferon after injection of mouse hepatitis virus type 3 in mice.

Authors:  L Schindler; H Engler; H Kirchner
Journal:  Infect Immun       Date:  1982-03       Impact factor: 3.441

5.  Lymphocyte-instructed monocyte induction of the coagulation pathways parallels the induction of hepatitis by the murine hepatitis virus.

Authors:  G A Levy; J L Leibowitz; T S Edgington
Journal:  Prog Liver Dis       Date:  1982

6.  Interferon production with multitray culture system on a large scale.

Authors:  J Utsumi; M Iizuka; S Kobayashi
Journal:  J Interferon Res       Date:  1984

7.  Difference in response to mouse hepatitis virus among susceptible mouse strains.

Authors:  F Taguchi; N Hirano; Y Kiuchi; K Fujiwara
Journal:  Jpn J Microbiol       Date:  1976-08

8.  Comparison of mouse hepatitis virus strains for pathogenicity in weanling mice infected by various routes.

Authors:  N Hirano; T Murakami; F Taguchi; K Fujiwara; M Matumoto
Journal:  Arch Virol       Date:  1981       Impact factor: 2.574

9.  Blocking of in vitro and in vivo susceptibility to mouse hepatitis virus.

Authors:  W Y Weiser; F B Bang
Journal:  J Exp Med       Date:  1977-11-01       Impact factor: 14.307

10.  The effect of mouse hepatitis virus infection on the microcirculation of the liver.

Authors:  G A Levy; P J MacPhee; L S Fung; M M Fisher; A M Rappaport
Journal:  Hepatology       Date:  1983 Nov-Dec       Impact factor: 17.425
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  6 in total

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Authors:  Kristine M Rose; Susan R Weiss
Journal:  Viruses       Date:  2009-12-01       Impact factor: 5.048

2.  Liver-specific alpha 2 interferon gene expression results in protection from induced hepatitis.

Authors:  L Aurisicchio; P Delmastro; V Salucci; O G Paz; P Rovere; G Ciliberto; N La Monica; F Palombo
Journal:  J Virol       Date:  2000-05       Impact factor: 5.103

3.  Murine coronavirus delays expression of a subset of interferon-stimulated genes.

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Review 4.  Fulminant hepatitis.

Authors:  S Sinclair; A Wakefield; G Levy
Journal:  Springer Semin Immunopathol       Date:  1990

5.  Regulated and prolonged expression of mIFN(alpha) in immunocompetent mice mediated by a helper-dependent adenovirus vector.

Authors:  L Aurisicchio; H Bujard; W Hillen; R Cortese; G Ciliberto; N La Monica; F Palombo
Journal:  Gene Ther       Date:  2001-12       Impact factor: 5.250

6.  Synergistic antiviral effect of a combination of mouse interferon-alpha and interferon-gamma on mouse hepatitis virus.

Authors:  Uichiro Fuchizaki; Shuichi Kaneko; Yasunari Nakamoto; Yoshihiro Sugiyama; Kenichi Imagawa; Mikio Kikuchi; Kenichi Kobayashi
Journal:  J Med Virol       Date:  2003-02       Impact factor: 2.327
  6 in total

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