Eujene Jung1, Jeong Ho Park2, Young Sun Ro3, Kyoung Jun Song2, Hyun Ho Ryu4, Seung Chul Lee5, Sang Do Shin6. 1. Department of Emergency Medicine, Chonnam National University Hospital, Gwang-ju, Republic of Korea. 2. Department of Emergency Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. 3. Laboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Institute, Seoul, Republic of Korea. 4. Department of Emergency Medicine, Chonnam National University Hospital, Gwang-ju, Republic of Korea. Electronic address: oriryu@hanmail.net. 5. Department of Emergency Medicine, Dongkuk University Ilsan Hospital, Goyang, Republic of Korea. 6. Department of Emergency Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address: shinsangdo@medimail.co.kr.
Abstract
OBJECTIVE: There are few studies on the effects hypertension has on survival outcomes in out-of-hospital-cardiac arrest (OHCA) patients, although hypertension is a major risk factor for the incidence of cardiac arrest. This study aims to investigate whether hypertension is associated with survival outcomes in cardiac arrest patients across age groups. METHODS: This study was conducted using the national cardiac arrest registry of OHCA patients who survived to hospital admission from 2012 to 2016. The clinical histories of hypertension were obtained from patients' medical records. The endpoint was cerebral performance category (CPC) 1 and 2 (good CPC) and survival to discharge. Multivariable logistic regression analysis was performed on the data collected. The final model with an interaction term was evaluated to compare the effects of hypertension across age groups. RESULTS: A total 11,610 patients (61.0% hypertensive patients and 39.0% non-hypertensive patients) were included. The group over 80 years old with hypertension were more likely to have good neurologic recovery (AOR 2.53 [1.43-4.50]) and those under 65 years old with hypertension were more likely to survive to hospital discharge with statistical significance (AOR 1.19 [1.04-1.35]). CONCLUSIONS: Hypertension does not imply poor survival outcomes independently for all ages, as those over 80 years of age can have rather good neurological outcomes.
OBJECTIVE: There are few studies on the effects hypertension has on survival outcomes in out-of-hospital-cardiac arrest (OHCA) patients, although hypertension is a major risk factor for the incidence of cardiac arrest. This study aims to investigate whether hypertension is associated with survival outcomes in cardiac arrestpatients across age groups. METHODS: This study was conducted using the national cardiac arrest registry of OHCA patients who survived to hospital admission from 2012 to 2016. The clinical histories of hypertension were obtained from patients' medical records. The endpoint was cerebral performance category (CPC) 1 and 2 (good CPC) and survival to discharge. Multivariable logistic regression analysis was performed on the data collected. The final model with an interaction term was evaluated to compare the effects of hypertension across age groups. RESULTS: A total 11,610 patients (61.0% hypertensivepatients and 39.0% non-hypertensivepatients) were included. The group over 80 years old with hypertension were more likely to have good neurologic recovery (AOR 2.53 [1.43-4.50]) and those under 65 years old with hypertension were more likely to survive to hospital discharge with statistical significance (AOR 1.19 [1.04-1.35]). CONCLUSIONS:Hypertension does not imply poor survival outcomes independently for all ages, as those over 80 years of age can have rather good neurological outcomes.
Authors: Talal Alnabelsi; Rahul Annabathula; Julie Shelton; Marc Paranzino; Sarah Price Faulkner; Matthew Cook; Adam J Dugan; Sethabhisha Nerusu; Susan S Smyth; Vedant A Gupta Journal: Resusc Plus Date: 2020-11-07