Literature DB >> 3002456

A novel, simple and rapid method for the isolation of mitochondria which exhibit respiratory control, from rat small intestinal mucosa.

C B Lawrence, N T Davies.   

Abstract

A method is described for the isolation of functional mitochondria from rat intestinal mucosa. Its novel feature is the removal of mucus from the initial homogenate by treatment with DEAE-cellulose. The preparations exhibited acceptable ADP:O ratios, high State-3 respiration rates, and respiratory control ratios in excess of 3 when succinate, beta-hydroxybutyrate, glutamate/malate and glutamine were test substrates.

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Year:  1986        PMID： 3002456     DOI： 10.1016/0005-2728(86)90157-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  4 in total

1.  Capillary electrophoresis monitors enhancement in subcellular reactive oxygen species production upon treatment with doxorubicin.

Authors:  Angela R Eder; Edgar A Arriaga
Journal:  Chem Res Toxicol       Date:  2006-09       Impact factor: 3.739

2.  Protective effect of Phyllanthus fraternus against mitochondrial dysfunction induced by co-administration of cisplatin and cyclophosphamide.

Authors:  Kavita K Kumari; O H Setty
Journal:  J Bioenerg Biomembr       Date:  2012-02-24       Impact factor: 2.945

3.  Protective efficacy of natansnin, a dibenzoyl glycoside from Salvinia natans against CCl4 induced oxidative stress and cellular degeneration in rat liver.

Authors:  Polimetla Srilaxmi; Gangadhara Reddy Sareddy; Polavarapu Bilhan Kavi Kishor; Oruganti Hussainaiah Setty; Phanithi Prakash Babu
Journal:  BMC Pharmacol       Date:  2010-10-12

4.  Alterations in enterocyte mitochondrial respiratory function and enzyme activities in gastrointestinal dysfunction following brain injury.

Authors:  Ke-Jun Zhu; Hong Huang; Hui Chu; Hang Yu; Shi-Ming Zhang
Journal:  World J Gastroenterol       Date:  2014-07-28       Impact factor: 5.742
  4 in total

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