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Literature DB >> 3002301

Persistent infection of rat insulinoma cells with Coxsackie B4 virus. Brief report.

J A Frank, E V Schmidt, R E Smith, C M Wilfert.

Abstract

Plaque purified Coxsackie B4 virus (CB4) caused a persistent infection of rat insulinoma (RIN) cells which lasted for the 70 day observation period. Infectious virus was produced and no cytopathic effect was observed. Indirect immunofluorescence and infectious center assays demonstrated that a majority of RIN cells were infected. Defective interfering particles were not demonstrated. Despite persistent infection, insulin synthesis by RIN cells was not altered.

Entities: Disease Species

Mesh：

Substances：
Insulin
Glucose

Year: 1986 PMID： 3002301 DOI： 10.1007/bf01310551

Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574

17 in total

1. Is mumps virus an etiologic factor in juvenile diabetes mellitus.

Authors: H A Sultz; B A Hart; M Zielezny; E R Schlesinger
Journal: J Pediatr Date: 1975-04 Impact factor: 4.406

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Authors: J E Craighead
Journal: N Engl J Med Date: 1978-12-28 Impact factor: 91.245

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Authors: D R Gamble
Journal: Postgrad Med J Date: 1974-08 Impact factor: 2.401

4. Type-specific reovirus antiserum blocks the cytotoxic T-cell-target cell interaction: evidence for the association of the viral hemagglutinin of a nonenveloped virus with the cell surface.

Authors: R Finberg; H L Weiner; S J Burakoff; B N Fields
Journal: Infect Immun Date: 1981-02 Impact factor: 3.441

Review 5. Insulin-dependent diabetes mellitus: the initial lesion.

Authors: G F Cahill; H O McDevitt
Journal: N Engl J Med Date: 1981-06-11 Impact factor: 91.245

6. Coxsackie B virus antibody responses in juvenile-onset diabetes mellitus.

Authors: C G Ray; J P Palmer; J R Crossley; R H Williams
Journal: Clin Endocrinol (Oxf) Date: 1980-04 Impact factor: 3.478

7. The role of host genetics in the pathogenesis of coxsackievirus infection in the pancreas of mice.

Authors: S R Webb; G E Madge
Journal: J Infect Dis Date: 1980-01 Impact factor: 5.226

8. Coxsackie viruses and diabetes mellitus.

Authors: D R Gamble; K W Taylor; H Cumming
Journal: Br Med J Date: 1973-11-03

9. Immunofluorescence staining of group B coxsackieviruses.

Authors: M L French; N J Schmidt; R W Emmons; E H Lennette
Journal: Appl Microbiol Date: 1972-01

10. Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor.

Authors: A F Gazdar; W L Chick; H K Oie; H L Sims; D L King; G C Weir; V Lauris
Journal: Proc Natl Acad Sci U S A Date: 1980-06 Impact factor: 11.205

6 in total

1. Persistent infection of human pancreatic islets by coxsackievirus B is associated with alpha interferon synthesis in beta cells.

Authors: W Chehadeh; J Kerr-Conte; F Pattou; G Alm; J Lefebvre; P Wattré; D Hober
Journal: J Virol Date: 2000-11 Impact factor: 5.103

Review 2. Virus infections: lessons from pancreas histology.

Authors: Francesco Dotta; Letizia Galleri; Guido Sebastiani; Francesco Vendrame
Journal: Curr Diab Rep Date: 2010-10 Impact factor: 4.810

3. Coxsackievirus B-3 selection of virus resistant Buffalo green monkey kidney cells and chromosome analysis of parental and resistant cells.

Authors: Y Cao; K H Walen; D Schnurr
Journal: Arch Virol Date: 1988 Impact factor: 2.574