Literature DB >> 30021480

Unusual Histopathological Findings in Appendectomy Specimens: A Retrospective Analysis of 2047 Cases.

Nurcan Unver1, Ganime Coban1, Dilek Sema Arıcı1, Nur Buyukpınarbasılı1, Zuhal Gucin1, Fatma Ümit Malya2, Oyku Izel Onaran3, Kıvanc Topalan4.   

Abstract

BACKGROUND: In this study, we retrospectively evaluated cases of patients who had undergone appendectomy in our hospital and aimed to present the efficiency of diagnostic tests and demographic data of cases. Pathological reports were analyzed for the following parameters: age, gender, and pathological diagnosis. In addition, the demographic and clinicopathologic characteristics of patients with unusual histopathologic findings were evaluated in detail, and reanalysis of archived resected appendix specimens was carried out.
METHODS: Files of 2047 patients (1329 males, 718 females, sex ratio: 1.85, age range: 1-87 years, mean age: 26, 50 years), who had been operated with a diagnosis of acute appendicitis in the emergency department of Bezmialem Vakıf University Medical Faculty from November 2011 to June 2014, were retrospectively evaluated.
RESULTS: Cases were separated into 2 groups. Cases with histopathologic examination reported as acute appendicitis constituted group 1 (n = 2013, 98.34%), and cases with pathologic findings other than acute appendicitis constituted group 2 (n = 34, 1.66%). The second group consisted of 8 low-grade mucinous neoplasms, 7 mucoceles, 6 carcinoid, 5 granulomatous inflammation, 4 intraluminal Enterobius vermicularis, 1 endometriosis externa, 1 adenocarcinoma infiltrated to serosa, 1 mesenteric cyst, and 1 low-grade adenocarcinoma formed in mucinous cystic neoplasm background.
CONCLUSION: Acute appendicitis is the most common emergency surgical condition. Although most of the resected appendectomy specimens showed typical histopathologic findings, some (1.66%) showed unusual histopathologic findings. Even if the macroscopic appearance of the specimen is normal or acute appendicitis, we suggest routine histopathological examination.

Entities:  

Keywords:  appendectomy specimens; appendicitis; carcinoid tumor; unusual findings

Mesh:

Year:  2018        PMID: 30021480     DOI: 10.1177/1066896918784650

Source DB:  PubMed          Journal:  Int J Surg Pathol        ISSN: 1066-8969            Impact factor:   1.271


  8 in total

1.  Histopathological features of incidental appendectomy specimens obtained from living liver donors.

Authors:  Sami Akbulut; Cemalettin Koç; Barış Sarıcı; Mehmet Özcan; Emine Şamdancı; Sezai Yılmaz
Journal:  Turk J Gastroenterol       Date:  2020-03       Impact factor: 1.852

2.  Neuroendocrine apendicopathy in morphologically normal appendices of patients with diagnosis of acute appendicitis: Diagnostic study.

Authors:  Andy Petroianu; Thiago Vinicius Villar Barroso; Marcelo Araújo Buzelin; Bárbara De Melo Theobaldo; Luciene Simões De Assis Tafuri
Journal:  Ann Med Surg (Lond)       Date:  2020-11-06

3.  The neglected role of Enterobius vermicularis in appendicitis: A systematic review and meta-analysis.

Authors:  Ali Taghipour; Meysam Olfatifar; Ehsan Javanmard; Mojtaba Norouzi; Hamed Mirjalali; Mohammad Reza Zali
Journal:  PLoS One       Date:  2020-04-23       Impact factor: 3.240

4.  Infrequent Offenders: Neuroendocrine Tumors and Cancers of the Appendix, Gallbladder, and Bile Duct.

Authors:  Kristen O'Hagan
Journal:  J Adv Pract Oncol       Date:  2021-04-01

5.  Unusual histopathological findings in appendectomy specimens with clinical diagnosis of acute appendicitis: A retrospective cohort analysis.

Authors:  Hamzeh Al-Balas; Raith S Al-Saffar; Mahmoud Al-Balas; Mohammad K M Al-Wiswasy; Ala'a Abu Salhiyeh; Yasmeen Al-Sharqi; Mustafa Saad Yousuf; Kamal Bani-Hani
Journal:  Ann Med Surg (Lond)       Date:  2021-08-21

Review 6.  Incidental neuroendocrine tumor of a complete subserosal appendix: an unusual presentation of a rare anatomical variation. A case report and review of literature.

Authors:  Stalin Isaías Cañizares Quisiguiña; Lucía Vanessa Guamán Maldonado; Iván Marcelo Hidalgo Jaramillo; Tatiana Paola Borja Herrera; Cecilia de Los Ángeles Carrión Guzmán
Journal:  BMC Surg       Date:  2021-12-16       Impact factor: 2.102

7.  Histopathological examination of cases with acute appendicitis, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia.

Authors:  Mai Kadi; Ali Nasr; Alaa A Shabkah; Rothana Alnahari; Afnan Alhawi; Romaysaa Alyamani; Abdulaziz M Saleem
Journal:  Ann Med Surg (Lond)       Date:  2022-08-19

Review 8.  Routine Histopathological Evaluation After Appendectomy: Is It Necessary? A Systematic Review.

Authors:  Kashish Malhotra; Ashvind Bawa
Journal:  Cureus       Date:  2020-08-18
  8 in total

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