Literature DB >> 30020413

Rapid Rebound of a Preexisting CXCR4-tropic Human Immunodeficiency Virus Variant After Allogeneic Transplantation With CCR5 Δ32 Homozygous Stem Cells.

Jens Verheyen1,2, Alexander Thielen2, Nadine Lübke3, Miriam Dirks1, Marek Widera1, Ulf Dittmer1, Lambros Kordelas4, Martin Däumer2, Dorien C M de Jong5, Annemarie M J Wensing5, Rolf Kaiser6, Monique Nijhuis5, Stefan Esser7.   

Abstract

Allogeneic stem cell transplantation (alloSCT) of homozygous CCR5 Δ32 stem cells once resulted in the cure of human immunodeficiency virus (HIV) infection. We have recently reported a viral breakthrough in a similar setting. Here, we demonstrate that the rapid rebound after alloSCT was related to a highly replicative CXCR4-tropic HIV variant, which could already be detected before alloSCT.

Entities:  

Mesh：

Substances：

Year:  2019        PMID： 30020413     DOI： 10.1093/cid/ciy565

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  21 in total

1.  Second example reported of a stem-cell transplant in the clinic leading to HIV remission.

Authors:  Timothy J Henrich
Journal:  Nature       Date:  2019-04       Impact factor: 49.962

2.  Immune Control of HIV.

Authors:  Muthukumar Balasubramaniam; Jui Pandhare; Chandravanu Dash
Journal:  J Life Sci (Westlake Village)       Date:  2019-06

Review 3.  HIV Eradication Strategies: Implications for the Central Nervous System.

Authors:  Rebecca T Veenhuis; Janice E Clements; Lucio Gama
Journal:  Curr HIV/AIDS Rep       Date:  2019-02       Impact factor: 5.071

Review 4.  Advances toward Curing HIV-1 Infection in Tissue Reservoirs.

Authors:  Lisa J Henderson; Lauren B Reoma; Joseph A Kovacs; Avindra Nath
Journal:  J Virol       Date:  2020-01-17       Impact factor: 5.103

Review 5.  On the Road to a HIV Cure: Moving Beyond Berlin and London.

Authors:  Nikolaus Jilg; Jonathan Z Li
Journal:  Infect Dis Clin North Am       Date:  2019-09       Impact factor: 5.982

Review 6.  Solid Organ Transplantation in HIV-Infected Recipients: History, Progress, and Frontiers.

Authors:  William A Werbel; Christine M Durand
Journal:  Curr HIV/AIDS Rep       Date:  2019-06       Impact factor: 5.071

7.  Allogeneic Hematopoietic Cell Transplant for HIV Patients with Hematologic Malignancies: The BMT CTN-0903/AMC-080 Trial.

Authors:  Richard F Ambinder; Juan Wu; Brent Logan; Christine M Durand; Ryan Shields; Uday R Popat; Richard F Little; Deborah K McMahon; Joshua Cyktor; John W Mellors; Ernesto Ayala; Lawrence D Kaplan; Ariela Noy; Richard J Jones; Alan Howard; Stephen J Forman; David Porter; Carlos Arce-Lara; Paul Shaughnessy; Lisa Sproat; Shahrukh K Hashmi; Adam M Mendizabal; Mary M Horowitz; Willis H Navarro; Joseph C Alvarnas
Journal:  Biol Blood Marrow Transplant       Date:  2019-07-04       Impact factor: 5.742

8.  Clones of infected cells arise early in HIV-infected individuals.

Authors:  John M Coffin; David W Wells; Jennifer M Zerbato; Joann D Kuruc; Shuang Guo; Brian T Luke; Joseph J Eron; Michael Bale; Jonathan Spindler; Francesco R Simonetti; Shawn Hill; Mary F Kearney; Frank Maldarelli; Xiaolin Wu; John W Mellors; Stephen H Hughes
Journal:  JCI Insight       Date:  2019-06-20

9.  Existence of Replication-Competent Minor Variants with Different Coreceptor Usage in Plasma from HIV-1-Infected Individuals.

Authors:  Yosuke Maeda; Taichiro Takemura; Takayuki Chikata; Takeo Kuwata; Hiromi Terasawa; Riito Fujimoto; Nozomi Kuse; Tomohiro Akahoshi; Hayato Murakoshi; Giang Van Tran; Yu Zhang; Chau Ha Pham; Anh Hong Quynh Pham; Kazuaki Monde; Tomohiro Sawa; Shuzo Matsushita; Trung Vu Nguyen; Kinh Van Nguyen; Futoshi Hasebe; Tetsu Yamashiro; Masafumi Takiguchi
Journal:  J Virol       Date:  2020-06-01       Impact factor: 5.103

Review 10.  Haemopoietic cell transplantation in patients living with HIV.

Authors:  Richard F Ambinder; Adam A Capoferri; Christine M Durand
Journal:  Lancet HIV       Date:  2020-08-10       Impact factor: 12.767
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.