Gengzhou Wei1,2, Xingyu Feng1, Wei Wang3, Yu Zhang4, Yujie Zeng5, Minhu Chen4, Ye Chen6, Jie Chen4, Zhiwei Zhou3, Yong Li1. 1. Department of General Surgery, Guangdong General Hospital; Guangdong Academy of Medical Sciences, Guangzhou, PR China. 2. Department of Medical College, South China University of Technology, Ganzhou, PR China. 3. Department of Gastric Surgery, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, PR China. 4. Department of Gastroenterology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, PR China. 5. Department of Gastrointestinal Surgery, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, PR China. 6. Department of Gastroenterology, Nanfang Hospital of Southern Medical University; Guangdong Provincial Key Laboratory of Gastroenterology, Guangzhou, PR China.
Abstract
AIM: This study was conducted to analyze the risk factors associated with lymph node metastasis in rectal neuroendocrine neoplasms (NENs). MATERIALS & METHODS: A total of 419 patients with rectal NENs were enrolled. A univariate analysis of risk factors of lymph node metastasis was conducted using a χ2 test, and a multivariate analysis was conducted using a logistic regression analysis. RESULTS: Univariate and multivariate regression analysis revealed that tumor size, G grade and the depth of tumor invasion were independent risk factors for lymph node metastasis (p < 0.05). CONCLUSION: Rectal NENs patients with a larger tumor size, deeper tumor invasion or a higher G grade had a higher risk of regional lymph node metastasis.
AIM: This study was conducted to analyze the risk factors associated with lymph node metastasis in rectal neuroendocrine neoplasms (NENs). MATERIALS & METHODS: A total of 419 patients with rectal NENs were enrolled. A univariate analysis of risk factors of lymph node metastasis was conducted using a χ2 test, and a multivariate analysis was conducted using a logistic regression analysis. RESULTS: Univariate and multivariate regression analysis revealed that tumor size, G grade and the depth of tumor invasion were independent risk factors for lymph node metastasis (p < 0.05). CONCLUSION: Rectal NENs patients with a larger tumor size, deeper tumor invasion or a higher G grade had a higher risk of regional lymph node metastasis.