Mikko Hirvonen1,2, Riitta Ojala2,3, Päivi Korhonen2,3, Paula Haataja2,3, Kai Eriksson2,4, Mika Gissler5,6,7, Tiina Luukkaala8,9, Outi Tammela2,3. 1. Department of Pediatrics, Central Finland Health Care District, Jyväskylä, Finland; mikko.hirvonen@ksshp.fi. 2. Tampere Center for Child Health Research and. 3. Departments of Pediatrics and. 4. Pediatric Neurology, and. 5. National Institute for Health and Welfare, Helsinki, Finland. 6. Research Centre for Child Psychiatry, University of Turku, Turku, Finland; and. 7. Division of Family Medicine, Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden. 8. School of Health Sciences, Faculty of Social Sciences, University of Tampere, Tampere, Finland. 9. Research and Innovation Center, Tampere University Hospital, Tampere, Finland.
Abstract
OBJECTIVES: Our aim was to determine and compare the incidences of sensory impairments among very preterm (VP) (<32 + 0/7 weeks), moderately preterm (MP) (32 + 0/7-33 + 6/7 weeks), late preterm (LP) (34 + 0/7-36 + 6/7 weeks), and term infants (≥37 weeks) and to establish risk factors of neurosensory disabilities. METHODS: This national register study included all live-born infants in Finland between 1991 and 2008. Infants who died before the age of 1 year, who had any major congenital anomaly, or had missing data were excluded (n = 21 007; 2.0%). A total of 1 018 256 infants were analyzed. Incidences of hearing loss, visual disturbances or blindness, other ophthalmologic disorders, and retinopathy of prematurity were determined for gestational age (GA) groups. Risk factors of hearing loss and visual disturbances or blindness were analyzed. RESULTS: The incidences of sensory impairments decreased with advancing GA at birth (P < .001). The most prominent factors associated with increased risks of hearing loss and visual impairment were intracranial hemorrhage and convulsions. VP (odds ratio [OR] 2.34; 95% confidence interval [CI] 1.75-3.14) and LP (OR 1.26; 95% CI 1.04-1.52) births were associated with an increased risk of hearing loss, and VP (OR 1.94; 95% CI 1.55-2.44), MP (OR 1.42; 95% CI 1.11-1.80), and LP (OR 1.31; 95% CI 1.16-1.49) births predicted an increased risk of visual impairment. CONCLUSIONS: Incidences of sensory impairment decreased with increasing GA at birth. The most prominent risk factors predictive of sensory disabilities were intracranial hemorrhage and convulsions. VP and LP births were associated with an increased risk of hearing loss, and VP, MP, and LP births were associated with an increased risk of visual impairment.
OBJECTIVES: Our aim was to determine and compare the incidences of sensory impairments among very preterm (VP) (<32 + 0/7 weeks), moderately preterm (MP) (32 + 0/7-33 + 6/7 weeks), late preterm (LP) (34 + 0/7-36 + 6/7 weeks), and term infants (≥37 weeks) and to establish risk factors of neurosensory disabilities. METHODS: This national register study included all live-born infants in Finland between 1991 and 2008. Infants who died before the age of 1 year, who had any major congenital anomaly, or had missing data were excluded (n = 21 007; 2.0%). A total of 1 018 256 infants were analyzed. Incidences of hearing loss, visual disturbances or blindness, other ophthalmologic disorders, and retinopathy of prematurity were determined for gestational age (GA) groups. Risk factors of hearing loss and visual disturbances or blindness were analyzed. RESULTS: The incidences of sensory impairments decreased with advancing GA at birth (P < .001). The most prominent factors associated with increased risks of hearing loss and visual impairment were intracranial hemorrhage and convulsions. VP (odds ratio [OR] 2.34; 95% confidence interval [CI] 1.75-3.14) and LP (OR 1.26; 95% CI 1.04-1.52) births were associated with an increased risk of hearing loss, and VP (OR 1.94; 95% CI 1.55-2.44), MP (OR 1.42; 95% CI 1.11-1.80), and LP (OR 1.31; 95% CI 1.16-1.49) births predicted an increased risk of visual impairment. CONCLUSIONS: Incidences of sensory impairment decreased with increasing GA at birth. The most prominent risk factors predictive of sensory disabilities were intracranial hemorrhage and convulsions. VP and LP births were associated with an increased risk of hearing loss, and VP, MP, and LP births were associated with an increased risk of visual impairment.
Authors: Peter J Anderson; Debora Marques de Miranda; Maicon Rodrigues Albuquerque; Marit Sæbø Indredavik; Kari Anne I Evensen; Ryan Van Lieshout; Saroj Saigal; H Gerry Taylor; Katri Raikkonen; Eero Kajantie; Neil Marlow; Samantha Johnson; Lianne J Woodward; Nicola Austin; Chiara Nosarti; Julia Jaekel; Dieter Wolke; Jeanie Ly Cheong; Alice Burnett; Karli Treyvaud; Katherine J Lee; Lex W Doyle Journal: EClinicalMedicine Date: 2021-11-27
Authors: Li Zhang; Nan-Nan Gao; Hui-Juan Liu; Qiong Wu; Ju Liu; Ting Zhang; Jin Sun; Jian-Hong Qi; Xiu-Yun Qiao; Yan Zhao; Yan Li Journal: Front Pediatr Date: 2022-06-13 Impact factor: 3.569
Authors: Amber L Cathey; Deborah J Watkins; Zaira Y Rosario; Carmen Vélez; Bhramar Mukherjee; Akram N Alshawabkeh; José F Cordero; John D Meeker Journal: Environ Health Perspect Date: 2022-03-25 Impact factor: 9.031