Literature DB >> 30014698

Nanocarbon-Based Glycoconjugates as Multivalent Inhibitors of Ebola Virus Infection.

Laura Rodríguez-Pérez1, Javier Ramos-Soriano1, Alfonso Pérez-Sánchez1, Beatriz M Illescas1, Antonio Muñoz1, Joanna Luczkowiak2, Fátima Lasala2, Javier Rojo3, Rafael Delgado2, Nazario Martín1,4.   

Abstract

SWCNTs, MWCNTs, and SWCNHs have been employed as virus-mimicking nanocarbon platforms for the multivalent presentation of carbohydrates in an artificial Ebola virus infection model assay. These carbon nanoforms have been chemically modified by the covalent attachment of glycodendrons and glycofullerenes using the CuAAC "click chemistry" approach. This modification dramatically increases the water solubility of these structurally different nanocarbons. Their efficiency in blocking DC-SIGN-mediated viral infection by an artificial Ebola virus has been tested in a cellular experimental assay, finding that glycoconjugates based on MWCNTs functionalized with glycofullerenes are potent inhibitors of viral infection.

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Year:  2018        PMID: 30014698     DOI: 10.1021/jacs.8b03847

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  12 in total

1.  Advances in Antiviral Material Development.

Authors:  Lili Liang; Ashiq Ahamed; Liya Ge; Xiaoxu Fu; Grzegorz Lisak
Journal:  Chempluschem       Date:  2020-08-21       Impact factor: 3.210

2.  Heteromultivalent topology-matched nanostructures as potent and broad-spectrum influenza A virus inhibitors.

Authors:  Chuanxiong Nie; Marlena Stadtmüller; Badri Parshad; Matthias Wallert; Vahid Ahmadi; Yannic Kerkhoff; Sumati Bhatia; Stephan Block; Chong Cheng; Thorsten Wolff; Rainer Haag
Journal:  Sci Adv       Date:  2021-01-01       Impact factor: 14.136

3.  Inhibitory effect and mechanism of gelatin stabilized ferrous sulfide nanoparticles on porcine reproductive and respiratory syndrome virus.

Authors:  Ting Tong; Shuangfei Deng; Xiaotong Zhang; Liurong Fang; Jiangong Liang; Shaobo Xiao
Journal:  J Nanobiotechnology       Date:  2022-02-05       Impact factor: 10.435

4.  Ramified derivatives of 5-(perylen-3-ylethynyl)uracil-1-acetic acid and their antiviral properties.

Authors:  Ksenia A Sapozhnikova; Nikita A Slesarchuk; Alexey A Orlov; Evgeny V Khvatov; Eugene V Radchenko; Alexey A Chistov; Alexey V Ustinov; Vladimir A Palyulin; Liubov I Kozlovskaya; Dmitry I Osolodkin; Vladimir A Korshun; Vladimir A Brylev
Journal:  RSC Adv       Date:  2019-08-20       Impact factor: 4.036

5.  High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus.

Authors:  Yanrong Zhou; Xiaohan Jiang; Ting Tong; Liurong Fang; Yuan Wu; Jiangong Liang; Shaobo Xiao
Journal:  RSC Adv       Date:  2020-04-07       Impact factor: 4.036

6.  Selective formation of dihydrofuran fused [60] fullerene derivatives by TEMPO mediated [3 + 2] cycloaddition of medium chain β-keto esters to C60.

Authors:  Jovana Jakšić; Aleksandra Mitrović; Zorana Tokić Vujošević; Miloš Milčić; Veselin Maslak
Journal:  RSC Adv       Date:  2021-09-02       Impact factor: 4.036

7.  Initiating Electron Transfer in Doubly Curved Nanographene Upon Supramolecular Complexation of C60.

Authors:  Simon Zank; Jesús M Fernández-García; Anton J Stasyuk; Alexander A Voityuk; Marcel Krug; Miquel Solà; Dirk M Guldi; Nazario Martín
Journal:  Angew Chem Int Ed Engl       Date:  2021-12-29       Impact factor: 16.823

8.  Formation and Photoinduced Electron Transfer in Porphyrin- and Phthalocyanine-Bearing N-Doped Graphene Hybrids Synthesized by Click Chemistry.

Authors:  Luis M Arellano; Habtom B Gobeze; Youngwoo Jang; Myriam Barrejón; Concepción Parejo; Julio C Álvarez; María J Gómez-Escalonilla; Ángela Sastre-Santos; Francis D'Souza; Fernando Langa
Journal:  Chemistry       Date:  2022-03-28       Impact factor: 5.020

Review 9.  Dendrimers and Dendritic Materials: From Laboratory to Medical Practice in Infectious Diseases.

Authors:  Miguel Ángel Ortega; Alberto Guzmán Merino; Oscar Fraile-Martínez; Judith Recio-Ruiz; Leonel Pekarek; Luis G Guijarro; Natalio García-Honduvilla; Melchor Álvarez-Mon; Julia Buján; Sandra García-Gallego
Journal:  Pharmaceutics       Date:  2020-09-14       Impact factor: 6.321

Review 10.  Glyconanomaterials for Human Virus Detection and Inhibition.

Authors:  Noelia Losada-Garcia; Carla Garcia-Sanz; Alicia Andreu; Trinidad Velasco-Torrijos; Jose M Palomo
Journal:  Nanomaterials (Basel)       Date:  2021-06-26       Impact factor: 5.076

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