| Literature DB >> 30012763 |
Anubhav Kanwar1,2,3, Jennifer L Cadnum2,3, Annette L Jencson2, Curtis J Donskey2,4.
Abstract
We examined the impact of systemic antibiotics on the burden of nasal Staphylococcus aureus in hospitalized patients. Of 1,482 patients, 237 (16%) had nasal methicillin-susceptible S. aureus (MSSA) and 92 (6%) had nasal methicillin-resistant S. aureus (MRSA) on admission. Treatment regimens that included agents with inhibitory activity against MRSA or MSSA significantly reduced the burden of carriage, whereas regimens lacking anti-MRSA activity, including fluoroquinolones, promoted MRSA overgrowth.Entities:
Keywords: Staphylococcus aureus; antibiotics; nasal burden
Mesh:
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Year: 2018 PMID: 30012763 PMCID: PMC6153793 DOI: 10.1128/AAC.00609-18
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191