Literature DB >> 30012680

Campylobacter fetus spondylodiscitis in a patient with HIV infection and restored CD4 count.

Dorien Laenens1, Mark Plazier2,3, Jeroen C H van der Hilst1,4, Peter Messiaen1,4.   

Abstract

Campylobacter fetus (C. fetus) is a rare condition and mostly seen in elderly or immunocompromised patients. We present the first case of C. fetus spondylodiscitis in a virologically suppressed HIV seropositive patient with low back pain. MRI was performed and showed spondylodiscitis of the L4-L5 region. Empirical antibiotic therapy with flucloxacillin was started after blood cultures were drawn and an image-guided disc biopsy was performed. Blood cultures remained negative. The anaerobic culture of the puncture biopsy of the disc revealed presence of C. fetus after which the antibiotic treatment was switched to ceftriaxone. Guided by the susceptibility results, the therapy was switched to ciprofloxacin orally for 6 weeks after which the patient made full clinical, biochemical and radiographic recovery. Since no other immune-deficient conditions were noted, it is important to highlight that patients with HIV infection with restored CD4 counts and complete virological suppression can still be susceptible for infections caused by rare pathogens. Low back pain should raise suspicion for these conditions and should be examined properly. © BMJ Publishing Group Limited 2018. No commercial re-use. See rights and permissions. Published by BMJ.

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Keywords:  Hiv / Aids; bone and joint Infections

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Year:  2018        PMID: 30012680     DOI: 10.1136/bcr-2018-225272

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  3 in total

1.  Campylobacter fetus spondylodiscitis: A case report and review of the literature.

Authors:  Daniel Olaiya; Rosemary Fok; Prithwiraj Chakrabarti; Himanshu Sharma; James Greig
Journal:  IDCases       Date:  2018-11-13

Review 2.  HIV and Mediterranean Zoonoses: A Review of the Literature.

Authors:  Ylenia Russotto; Cristina Micali; Giovanni Francesco Pellicanò; Giuseppe Nunnari; Emmanuele Venanzi Rullo
Journal:  Infect Dis Rep       Date:  2022-09-16

3.  Case Report: Campylobacter fetus caused pyogenic spondylodiscitis with a presentation of cauda equina syndrome after instrumented lumbar fusion surgery.

Authors:  Matevž Topolovec; Nataša Faganeli; Peter Brumat
Journal:  Front Surg       Date:  2022-10-04
  3 in total

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