Blood Cholesterol Monitoring With Smartphone as Miniaturized Electrochemical Analyzer for Cardiovascular Disease Prevention.

Currently, cardiovascular diseases become one of the major threat to human's life. The early prevention of cardiovascular diseases plays a critical role in the healthcare engineering. Point of care monitoring the blood lipid level is capable of making the positive contribution to the prevention of cardiovascular disease. Ubiquitous smartphones paved the way as the flexible and widespread platform for the interaction of various health information. In this manuscript, we report the world's first medical smartphone as an electrochemical analyzer for blood lipid monitoring. Integrating an electrochemical analyzer into a smartphone allows us to measure the current generated by the enzymatic reaction with the total cholesterol test strip. The disposable test strip is used to convert the biochemical signal to electrical signal through the electrochemical reaction. The proposed medical smartphone can provide accurate evaluation of patient's blood lipid level as compared to the clinical biochemical analyzer. The proposed medical smartphone system is a promising platform as a point-of-care device for blood total cholesterol (TC) monitoring, which can be applied for long-term prevention of cardiovascular disease due to its portability, reliability, lower cost, convenience, and internet-based medical data interaction.