Literature DB >> 30009712

A form of Autoimmune Diabetes in Adults Named LADA - An Update on Essential Features and Controversies.

Valdemar Grill1, Bjørn O Åsvold2,3.   

Abstract

Latent Autoimmune Diabetes in the Adult, LADA has been investigated less than "classical" type 1 and type 2 diabetes and the criteria for and the relevance of a LADA diagnosis has been challenged. Despite the absence of a genetic background that is exclusive to LADA, this form of diabetes displays phenotypic characteristics that distinguish it from other forms of diabetes. LADA is heterogeneous in terms of the impact of autoimmunity and lifestyle factors, something that poses problems as to therapy and follow-up perhaps particularly in those with marginal positivity. Yet, there appears to be clear clinical utility in classifying individuals as LADA. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities:  

Keywords:  Autoantibodies; GADA; glutamic acid decarboxylase; insulin secretion; type 1 diabetes; type 2 diabetes.

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Year:  2019        PMID: 30009712     DOI: 10.2174/1573399814666180716152342

Source DB:  PubMed          Journal:  Curr Diabetes Rev        ISSN: 1573-3998


  1 in total

1.  Latent Autoimmune Diabetes in Adults: Background, Safety and Feasibility of an Ongoing Pilot Study With Intra-Lymphatic Injections of GAD-Alum and Oral Vitamin D.

Authors:  Anneli Björklund; Ingrid K Hals; Valdemar Grill; Johnny Ludvigsson
Journal:  Front Endocrinol (Lausanne)       Date:  2022-07-18       Impact factor: 6.055

  1 in total

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