| Literature DB >> 30009712 |
Valdemar Grill1, Bjørn O Åsvold2,3.
Abstract
Latent Autoimmune Diabetes in the Adult, LADA has been investigated less than "classical" type 1 and type 2 diabetes and the criteria for and the relevance of a LADA diagnosis has been challenged. Despite the absence of a genetic background that is exclusive to LADA, this form of diabetes displays phenotypic characteristics that distinguish it from other forms of diabetes. LADA is heterogeneous in terms of the impact of autoimmunity and lifestyle factors, something that poses problems as to therapy and follow-up perhaps particularly in those with marginal positivity. Yet, there appears to be clear clinical utility in classifying individuals as LADA. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Entities:
Keywords: Autoantibodies; GADA; glutamic acid decarboxylase; insulin secretion; type 1 diabetes; type 2 diabetes.
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Year: 2019 PMID: 30009712 DOI: 10.2174/1573399814666180716152342
Source DB: PubMed Journal: Curr Diabetes Rev ISSN: 1573-3998