| Literature DB >> 30009294 |
Rintaro Iwata Hara1, Yusuke Maeda, Haruna Fujimaki, Takeshi Wada.
Abstract
This study assessed the effects of artificial cationic oligopeptides on a DNA/RNA hybrid duplex. An oligopeptide containing the octamer of l-2,4-diaminobutyric acid (Dab8) was found to enhance both the RNase A resistance and RNase H activity of the DNA/RNA hybrid, which are important for developing nucleic acid drugs.Entities:
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Year: 2018 PMID: 30009294 DOI: 10.1039/c8cc04082f
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222