Literature DB >> 3000815

TRH analogue with C-terminal thioamide group. Synthesis, receptor binding, TSH-releasing activity and alpha-MSH-releasing activity.

M Kruszyński, G Kupryszewski, U Ragnarsson, M Alexandrova, V Strbak, M C Tonon, H Vaudry.   

Abstract

A new TRH analogue containing a C-terminal thioamide group was synthesized. This peptide was shown to have receptor-binding affinity, and TSH- as well as alpha-MSH-releasing activities very similar to native TRH.

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Year:  1985        PMID： 3000815     DOI： 10.1007/bf01964815

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  [Control of pituitary secretion of melanotropin in an anuran amphibian by thyrotropin releasing factor (TRH). Study in vitro].

Authors:  H Vaudry; M C Trochard; F Leboulenger; R Vaillant
Journal:  C R Acad Hebd Seances Acad Sci D       Date:  1977-03-14

Review 2.  Hypothalamic regulatory hormones.

Authors:  A V Schally; A Arimura; A J Kastin
Journal:  Science       Date:  1973-01-26       Impact factor: 47.728

3.  Carboxyl-catalyzed intramolecular aminolysis. A side reaction in solid-phase peptide synthesis.

Authors:  B F Gisin; R B Merrifield
Journal:  J Am Chem Soc       Date:  1972-05-03       Impact factor: 15.419

4.  [A new method for synthesis of peptides: activation of the carboxyl group with dicyclohexylcarbodiimide using 1-hydroxybenzotriazoles as additives].

Authors:  W König; R Geiger
Journal:  Chem Ber       Date:  1970

5.  Thyrotropin releasing hormone and its analogues I. New syntheses and biological properties of TRH (Pro-NH-NH2)3-TRH and (2-Picolyl)-TRH.

Authors:  J Bobrowska; P Leroux; E Maliński; J Przybylski; J Szafranek; M C Tonon; H Vaudry; G Kupryszewski
Journal:  Mater Med Pol       Date:  1980 Jan-Jun

6.  Prolactin and thyrotropin release in man by synthetic pyroglutamyl-histidyl-prolinamide.

Authors:  C Y Bowers; H G Friesen; P Hwang; H J Guyda; K Folkers
Journal:  Biochem Biophys Res Commun       Date:  1971-11       Impact factor: 3.575

7.  Discovery of modification of the synthetic tripeptide-sequence of the thyrotropin releasing hormone having activity.

Authors:  K Folkers; F Enzmann; J Boler; C Y Bowers; A V Schally
Journal:  Biochem Biophys Res Commun       Date:  1969-09-24       Impact factor: 3.575

8.  [Synthetic polypeptide derivatives with thyrotropin releasing factor hypophysiotropic activity].

Authors:  R Burgus; T F Dunn; D N Ward; W Vale; M Amoss; R Guillemin
Journal:  C R Acad Hebd Seances Acad Sci D       Date:  1969-04-21

9.  Synthesis and some pharmacological properties of (1-deamino,9-thioglycine)oxytocin.

Authors:  W C Jones; J J Nestor; V Du Vigneaud
Journal:  J Am Chem Soc       Date:  1973-08-22       Impact factor: 15.419

10.  Synthesis of thyrotropin-releasing hormone analogues with selective central nervous system effects.

Authors:  R F Nutt; F W Holly; C Homnick; R Hirschmann; D F Veber; B H Arison
Journal:  J Med Chem       Date:  1981-06       Impact factor: 7.446
  10 in total

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