| Literature DB >> 3000762 |
K Trenfield, P B Spradbrow, B Vanselow.
Abstract
DNA was extracted from 14 equine sarcoids, electrophoresed and hybridised with a radioactively labelled probe of bovine papillomavirus type I (BPV 1) DNA under conditions of low stringency. Twelve sarcoids contained sequences of DNA that hybridised with the probe and that comigrated with BPV 2 DNA. The viral DNAs in four of these sarcoids differed from BPV 1 and BPV 2 DNA on restriction endonuclease analysis. One of four cell lines derived from sarcoids also contained BPV 1 related DNA. The results confirm the frequent presence in equine sarcoids of unintegrated papillomaviral DNA and suggest a role for papillomavirus infection in this disease.Entities:
Mesh：
Substances：
Year: 1985 PMID： 3000762 DOI： 10.1111/j.2042-3306.1985.tb02553.x
Source DB: PubMed Journal: Equine Vet J ISSN： 0425-1644 Impact factor: 2.888