Literature DB >> 30006842

Diagnosis and treatment of gastric antral webs in pediatric patients.

Ruchi Amin1, Alfonso M Martinez2, Marjorie J Arca3.   

Abstract

BACKGROUND: Gastric antral webs are mucosal structures, varying from fenestrated diaphragms to mucosal crescents, resulting in varying degrees of foregut obstruction. Patients commonly present with vomiting, failure to thrive, and abdominal pain. Prevalence is unknown, and diagnosis can be difficult.
METHODS: We performed an IRB-approved retrospective review of patients from 4/1/2015-4/1/2018 at a Level I Children's Surgery Center undergoing gastric antral web resection. Data obtained included demographics, preoperative workup, surgical repair, and outcomes.
RESULTS: Twenty-one patients were identified; 67% were male with an average age of 30 months at diagnosis. Initial diagnosis was established by a combination of fluoroscopy and esophagogastroduodenoscopy (EGD) in all patients. Patients presented with emesis (76%), failure to thrive (57%), need for post-pyloric tube feeds (33%), and abdominal pain (14%). Web localization without intraoperative EGD (n = 3) was initially challenging. As a result, intraoperative EGD was combined with operative antral web resection to facilitate web localization (n = 18). Web marking techniques have evolved from marking with suture (n = 1) and tattoo (n = 2), to endoscopic clip application (n = 12). All 21 patients underwent web resection, 2 were performed laparoscopically. Twenty underwent Heineke-Mikulicz pyloroplasty during the initial surgery. Average length of stay was 5.5 days. There were no intraoperative complications or deaths. Permanent symptom resolution occurred in 90% of patients immediately, with a statistically significant decrease in emesis (p < 0.001), failure to thrive (p < 0.001), and need for post-pyloric tube feeding (p = 0.009) within 6 months of surgery.
CONCLUSION: Gastric antral webs should be considered in the differential diagnosis for a child with persistent vomiting. Web resection with the use of intraoperative endoscopic localization can result in permanent symptom resolution in the majority of these patients.

Entities:  

Keywords:  Endoscopy; Gastric antral web; Heineke-Mikulicz pyloroplasty

Mesh:

Year:  2018        PMID: 30006842     DOI: 10.1007/s00464-018-6338-2

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  10 in total

1.  Duodenal atresia and gastric antral web. A significant lesson to learn.

Authors:  C Ferguson; A Morabito; A Bianchi
Journal:  Eur J Pediatr Surg       Date:  2004-04       Impact factor: 2.191

2.  Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

Authors:  Paul A Harris; Robert Taylor; Robert Thielke; Jonathon Payne; Nathaniel Gonzalez; Jose G Conde
Journal:  J Biomed Inform       Date:  2008-09-30       Impact factor: 6.317

3.  Gastric antral web: a rare cause of gastric outlet obstruction treated with endoscopic therapy.

Authors:  Wajeeh Salah; Todd H Baron
Journal:  Gastrointest Endosc       Date:  2013-09       Impact factor: 9.427

4.  Resolution of symptomatic GERD and delayed gastric emptying after endoscopic ablation of antral diaphragm (web).

Authors:  M E Maldonado; J J Mamel; M C Johnson
Journal:  Gastrointest Endosc       Date:  1998-10       Impact factor: 9.427

5.  Endoscopic diagnosis of antral webs in children.

Authors:  Julia Fritz; Alfonso Martinez; Marjorie Arca; Diana Lerner
Journal:  Endoscopy       Date:  2017-01-09       Impact factor: 10.093

6.  Endoscopic laser treatment of an obstructing antral web.

Authors:  F H Al-Kawas
Journal:  Gastrointest Endosc       Date:  1988 Jul-Aug       Impact factor: 9.427

7.  Gastric outlet obstruction caused by prepyloric mucosal diaphragm mimicking duodenal ulcer: a case report.

Authors:  A Nissan; D Seror; R Udassin
Journal:  Acta Paediatr       Date:  1997-01       Impact factor: 2.299

8.  Operationalizing quality improvement in a pediatric surgical practice.

Authors:  Marjorie J Arca; Jessica Enters; Melissa Christensen; Paul Jeziorczak; Thomas T Sato; Robert Thielke; Keith T Oldham
Journal:  J Pediatr Surg       Date:  2013-10-05       Impact factor: 2.545

9.  Prepyloric gastric antral web: a puzzling epidemic.

Authors:  M J Bell; J L Ternberg; J P Keating; S Moedjona; W McAlister; G D Shackelford
Journal:  J Pediatr Surg       Date:  1978-06       Impact factor: 2.545

10.  Gastric antral webs in adults: A case series characterizing their clinical presentation and management in the modern endoscopic era.

Authors:  Shannon J Morales; Neha Nigam; Walid M Chalhoub; Dalia I Abdelaziz; James H Lewis; Stanley B Benjamin
Journal:  World J Gastrointest Endosc       Date:  2017-01-16
  10 in total
  1 in total

1.  Clinical Presentations, Diagnosis, and Management for Pediatric Antral Web-A 20-Year Experience of a Referral Center.

Authors:  Pai-Jui Yeh; Hsun-Chin Chao; Chien-Chang Chen; Jin-Yao Lai; Ming-Wei Lai
Journal:  Front Pediatr       Date:  2021-12-14       Impact factor: 3.418

  1 in total

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