Francisca S Rodriguez1, María P Aranda2, Donald A Lloyd3, William A Vega3. 1. USC Edward R. Roybal Institute on Aging, University of Southern California, Los Angeles, CA; Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Germany; Center for Cognitive Science, University of Kaiserslautern, Kaiserslautern, Germany. Electronic address: frodrigu@rhrk.uni-kl.de. 2. USC Edward R. Roybal Institute on Aging, University of Southern California, Los Angeles, CA; Suzanne Dworak-Peck School of Social Work, University of Southern California, Los Angeles, CA. 3. USC Edward R. Roybal Institute on Aging, University of Southern California, Los Angeles, CA.
Abstract
INTRODUCTION: As higher dementia prevalence in ethnic minority groups could be attributed to low education, we studied individuals with low education and explored potential factors driving dementia disparities. METHODS: We examined differences in dementia risk between low-educated non-Hispanic whites, Hispanics, and African Americans, and the impact of lifetime risk factors using data from the nationally representative Aging, Demographics, and Memory Study (N = 819). RESULTS: As indicated by Cox regression modeling, dementia risk of low-educated individuals was not significantly different between ethnic groups but was related to having an APOE e4 allele (hazard ratio [HR] 1.89), depression (HR 1.67), stroke (HR 1.60), and smoking (HR 1.32). Further, even in people with low education, every additional year of education decreased dementia risk (HR 0.95). DISCUSSION: Our findings imply that higher dementia prevalence in ethnic minorities may be attributable to low education, especially among Hispanics, in addition to other risk factors.
INTRODUCTION: As higher dementia prevalence in ethnic minority groups could be attributed to low education, we studied individuals with low education and explored potential factors driving dementia disparities. METHODS: We examined differences in dementia risk between low-educated non-Hispanic whites, Hispanics, and African Americans, and the impact of lifetime risk factors using data from the nationally representative Aging, Demographics, and Memory Study (N = 819). RESULTS: As indicated by Cox regression modeling, dementia risk of low-educated individuals was not significantly different between ethnic groups but was related to having an APOE e4 allele (hazard ratio [HR] 1.89), depression (HR 1.67), stroke (HR 1.60), and smoking (HR 1.32). Further, even in people with low education, every additional year of education decreased dementia risk (HR 0.95). DISCUSSION: Our findings imply that higher dementia prevalence in ethnic minorities may be attributable to low education, especially among Hispanics, in addition to other risk factors.
Authors: Rachel L Peterson; Kristen M George; Lisa L Barnes; Paola Gilsanz; Elizabeth Rose Mayeda; M Maria Glymour; Dan M Mungas; Rachel A Whitmer Journal: JAMA Netw Open Date: 2021-10-01
Authors: María P Aranda; Ian N Kremer; Ladson Hinton; Julie Zissimopoulos; Rachel A Whitmer; Cynthia Huling Hummel; Laura Trejo; Chanee Fabius Journal: J Am Geriatr Soc Date: 2021-07 Impact factor: 7.538