Literature DB >> 300057

Immunodeficiency with lymphoid hyperplasia.

I Mutz, W Stögmann.   

Abstract

A 2 1/2-year-old boy presented with recurrent respiratory tract infections, generalized lymphadenopathy and hepatosplenomegaly. Immunologic evaluation revealed a deficiency of humoral immunity. Repeated lymph node biopsies during a 10-year follow-up constantly showed excessive follicular hyperplasia with huge germinal centers consisting of germinoblasts, but lacking plasma cells. The disease can be interpreted as a subtype of the common variable immunodeficiency in which the commutation of germinoblasts to plasma cells in the evolution of B cells is blocked.

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Year:  1977        PMID： 300057     DOI： 10.1007/bf00452112

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  13 in total

1.  Meeting report of the Second International Workshop on Primary Immunodeficiency Disease in Man held in St. Petersburg, Florida, February, 1973.

Authors:  M D Cooper; W P Faulk; H H Fudenberg; R A Good; W Hitzig; H G Kunkel; I M Roitt; F S Rosen; M Seligmann; J F Soothill
Journal:  Clin Immunol Immunopathol       Date:  1974-04

2.  Heterogeneity of "acquired" or common variable agammaglobulinemia.

Authors:  R S Geha; E Schneeberger; E Merler; F S Rosen
Journal:  N Engl J Med       Date:  1974-07-04       Impact factor: 91.245

3.  Rosette-forming cells, immunologic deficiency diseases and transfer factor.

Authors:  J Wybran; A S Levin; L E Spitler; H H Fudenberg
Journal:  N Engl J Med       Date:  1973-04-05       Impact factor: 91.245

4.  Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinaemia.

Authors:  T A Waldmann; M Durm; S Broder; M Blackman; R M Blaese; W Strober
Journal:  Lancet       Date:  1974-09-14       Impact factor: 79.321

5.  Immunoglobulins on the surface of lymphocytes in fifty patients with primary immunodeficiency diseases.

Authors:  J L Preud'Homme; C Griscelli; M Seligmann
Journal:  Clin Immunol Immunopathol       Date:  1973-01

6.  Primary antibody deficiency syndrome of adult onset. Evidence for genetic transmission.

Authors:  A Cruchaud; M Robert; J P Girard; C Laperrouza; L Rivat; C Ropartz
Journal:  Am J Med       Date:  1970-04       Impact factor: 4.965

Review 7.  B and T cell markers in human proliferative blood diseases and primary immunodeficiencies, with special reference to membrane bound immunoglobulins.

Authors:  M Seligmann; J L Preud'Homme; J C Brouet
Journal:  Transplant Rev       Date:  1973

8.  Human bone marrow lymphocytes: B and T cell precursors and subpopulations.

Authors:  N L Abdou; J B Alavi; N I Abdou
Journal:  Blood       Date:  1976-03       Impact factor: 22.113

9.  B and T lymphocytes in primary immunodeficiency disease in man.

Authors:  K J Gajl-Peczalska; B H Park; W D Biggar; R A Good
Journal:  J Clin Invest       Date:  1973-04       Impact factor: 14.808

10.  Lymphocytes in patients with variable immunodeficiency and panhypogammaglobulinemia. Evaluation of B and T cell surface markers and a proposed classification.

Authors:  H B Dickler; N F Adkinson; R I Fisher; W D Terry
Journal:  J Clin Invest       Date:  1974-03       Impact factor: 14.808
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