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Literature DB >> 30003624

Time Travels: A 40-Year Journey from Drosophila's Clock Mutants to Human Circadian Disorders (Nobel Lecture).

Abstract

Living organisms have a biological clock that helps to prepare our physiology for the fluctuations of the day. Key research to elucidate the biological mechanisms of this regular adaptation, referred to as the circadian rhythm, is described by M. W. Young in his Nobel lecture.

Entities: Disease Species

Keywords: Drosophila; biological clock; circadian rhythm; genetic disorders; molecular genetics

Mesh：

Substances：

Year: 2018 PMID： 30003624 DOI： 10.1002/anie.201803337

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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Cited

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Time Travels: A 40-Year Journey from Drosophila's Clock Mutants to Human Circadian Disorders (Nobel Lecture).

1. The Expression of the Emotions in Man and Fruit Flies.

2. Molecular Oscillator Affects Susceptibility of Caterpillars to Insecticides: Studies on the Egyptian Cotton Leaf Worm-Spodoptera littoralis (Lepidoptera: Noctuidae).

3. Expansion of the circadian transcriptome in Brassica rapa and genome-wide diversification of paralog expression patterns.

4. The 50th anniversary of the Konopka and Benzer 1971 paper in PNAS: "Clock Mutants of Drosophila melanogaster".

Review 5. Rare Genetic Diseases: Nature's Experiments on Human Development.

6. Predictability of individual circadian phase during daily routine for medical applications of circadian clocks.

Review 7. Disturbance of the Circadian System in Shift Work and Its Health Impact.

Review 8. Metabolic consequences of obesity and type 2 diabetes: Balancing genes and environment for personalized care.

Review 9. The aryl hydrocarbon receptor as a model PAS sensor.