| Literature DB >> 30003615 |
Mark D Tarn1,2,3, Nuray Yavuzkanat Kızılyer4,5, Mohammad M N Esfahani1,6, Pankaj Joshi4, Nathaniel J Brown6, Nicole Pamme2, David G Jenkins4, Stephen J Archibald1,2.
Abstract
A miniaturized radio-HPLC detector has been developed comprising a microfluidic device fabricated from plastic scintillator in combination with a silicon photomultiplier light sensor, and tested with samples containing a positron-emitting radionuclide, [18 F]fluoride. This cost-effective, small footprint analytical tool is ideal for incorporation into integrated quality control systems for the testing of positron emission tomography (PET) radiopharmaceuticals to good manufacturing practice (GMP) standards.Entities:
Keywords: liquid chromatography; microfluidics; plastic scintillator; positron emission tomography; radiopharmaceuticals; silicon photomultiplier
Year: 2018 PMID： 30003615 DOI： 10.1002/chem.201802395
Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236