Literature DB >> 30002737

Correction to: Plasma fatty acid levels and gene expression related to lipid metabolism in peripheral blood mononuclear cells: a cross-sectional study in healthy subjects.

Sunniva V Larsen1, Kirsten B Holven1,2, Inger Ottestad1, Kine N Dagsland3, Mari C W Myhrstad3, Stine M Ulven1.   

Abstract

[This corrects the article DOI: 10.1186/s12263-018-0600-z.].

Entities:  

Year:  2018        PMID: 30002737      PMCID: PMC6033280          DOI: 10.1186/s12263-018-0604-8

Source DB:  PubMed          Journal:  Genes Nutr        ISSN: 1555-8932            Impact factor:   5.523


Correction

Unfortunately, after publication of this article [1], it was noticed that some corrections to Table 2 were not carried out. The corrected Table 2 can be seen below and the original article has also been updated to reflect this.
Table 2

Characteristics and plasma fatty acid profile of subjects in the highest and lowest tertiles

n-6 leveln-3 levelSFA/PUFA ratio
Highest tertileLowest tertile P Highest tertileLowest tertile P Highest tertileLowest tertile P
(n 18)(n 18)(n 18)(n 18)(n 18)(n 18)
Male/female5/135/133/155/135/136/12
Age (years)25 (23–33)25 (21–29)0.3125 (21–31)24 (21–28)0.8025 (22–29)28 (23.0–32.8)0.38
BMI (kg/m2)22.5 ± 2.922.6 ± 2.60.9422.2 ± 222.7 ± 3.30.5723.3 ± 2.722.6 ± 2.60.41
Total-C (mmol/l)4.9 ± 0.94.7 ± 1.10.654.9 ± 14.9 ± 10.964.7 ± 0.85.0 ± 0.90.25
LDL-C (mmol/l)2.7 ± 0.82.6 ± 0.90.792.6 ± 0.92.8 ± 0.60.712.5 ± 0.62.8 ± 0.90.16
HDL-C (mmol/l)1.6 ± 0.41.4 ± 0.30.151.6 ± 0.31.4 ± 0.40.281.5 ± 0.41.6 ± 0.30.74
TG (mmol/l)0.8 (0.6–0.9)1.2 (0.9–1.7) 0.01 0.8 (0.6–1.1)1.0 (0.7–1.2)0.301.1 (0.8–1.6)0.8 (0.6–0.9) 0.01
Lymphocytes (%)38.4 ± 6.843.0 ± 8.50.0842.2 ± 10.037.6 ± 40.0942.1 ± 8.737.4 ± 8.40.11
Monocytes (%)8.5 ± 1.88.1 ± 1.90.498.1 ± 1.78.6 ± 2.30.428.8 ± 2.28.48 ± 2.00.71
Plasma level of fatty (wt%)
Total SFA29.4 (28.8–30.5)32.1 (31.1–33.2) < 0.01 30.7 (29.3–32.3)30.8 (29.8–31.8)0.7832.6 (31.5–33.2)29.1 (28.7–29.5) < 0.01
Myristic acid (14:0)0.6 (0.6–1.0)1.0 (0.8–1.2) < 0.01 0.8 (0.6–1.1)0.9 (0.7–1.1)0.571.1 (0.9–1.2)0.6 (0.6–0.9) < 0.01
Palmitic acid (16:0)20.5 (20.2–21.6)23.4 (21.4–24.2) < 0.01 20.9 (20.4–23.7)21.5 (20.9–22.6)0.3923.9 (21.8–24.5)20.4 (20.2–20.7) < 0.01
Stearic acid (18:0)8.1 ± 0.78.1 ± 1.10.868.2 ± 1.18.0 ± 1.00.658.0 ± 1.17.7 ± 0.80.37
Total n-638.6 ± 1.330.3 ± 2.9 < 0.01 31.0 ± 4.031.5 ± 4.50.7430.8 ± 3.438.0 ± 2.0 < 0.01
LA (18:2n-6)32.3 ± 1.624.9 ± 2.5 < 0.01 27.8 ± 3.829.2 ± 4.10.2924.8 ± 2.531.8 ± 2.1 < 0.01
AA (20:4n-6)6.2 ± 1.15.4 ± 0.9 0.02 5.8 ± 0.76.2 ± 1.20.325.9 ± 1.36.2 ± 1. 10.58
Total n-35.8 ± 2.57.0 ± 2.30.129.0 ± 0.93.6 ± 0.49 < 0.01 6.1 ± 2.56.8 ± 2.40.44
ALA (18:3n- 3)0.5 (0.5–0.6)0.5 (0.4–0.6)0.460.5 (0.5–0.6)0.5 (0.5–0.6)0.790.5 (0.5–0.6)0.5 (0.5–0.5)0.95
EPA (20:5n-3)1.7 (0.6–2.3)2.4 (1.8–2.9)0.143.2 (2.8–3.7)0.6 (0.5–0.6) < 0.01 2.0 (0.7–2.6)2.2 (1.3–3.2)0.46
DPA (22:5n-3)0.6 ± 0.10.7 ± 0.20.260.8 ± 0.10.5 ± 0.1 < 0.01 0.6 ± 0.20.6 ± 0.10.80
DHA (22:6n-3)3.0 (1.9–4.1)4.0 (3.1–4.1)0.144.3 (4.1–4.7)1.9 (1.8–2.1) < 0.01 3.5 (2.0–4.1)3.3 (2.8–4.3)0.48
Total PUFA43.8 (42.1–47.3)38.6 (35.8–39.7) < 0.01 42.2 (39.5–46.7)40.4 (37.7–41.5) 0.05 37.8 (35.8–39.1)44.6 (43.1–47.3) < 0.01
SFA to PUFA ratio0.7 (0.6–0.7)0.8 (0.8–0.9) < 0.01 0.7 (0.6–0.8)0.8 (0.7–0.8)0.130.9 (0.8–0.9)0.7 (0.6–0.7) < 0.01

Lymphocytes and monocytes are given as percentage of total white cell count. Differences between tertiles were analyzed using the independent samples t test when normally distributed or the Mann-Whitney U test when not normally distributed. P values < 0.05 were considered significant. Values are presented as mean ± SD or medians and 25th–75th percentile

BMI body mass index, Total-C total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, TG triglycerides, SFA saturated fatty acid, LA linoleic acid, AA arachidonic acid, ALA alpha-linolenic acid, EPA eicosapentaenoic acid, DPA docosapentaenoic acid, DHA docosahexaenoic acid, PUFA polyunsaturated fatty acid

Characteristics and plasma fatty acid profile of subjects in the highest and lowest tertiles Lymphocytes and monocytes are given as percentage of total white cell count. Differences between tertiles were analyzed using the independent samples t test when normally distributed or the Mann-Whitney U test when not normally distributed. P values < 0.05 were considered significant. Values are presented as mean ± SD or medians and 25th–75th percentile BMI body mass index, Total-C total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, TG triglycerides, SFA saturated fatty acid, LA linoleic acid, AA arachidonic acid, ALA alpha-linolenic acid, EPA eicosapentaenoic acid, DPA docosapentaenoic acid, DHA docosahexaenoic acid, PUFA polyunsaturated fatty acid
  1 in total

1.  Plasma fatty acid levels and gene expression related to lipid metabolism in peripheral blood mononuclear cells: a cross-sectional study in healthy subjects.

Authors:  Sunniva V Larsen; Kirsten B Holven; Inger Ottestad; Kine N Dagsland; Mari C W Myhrstad; Stine M Ulven
Journal:  Genes Nutr       Date:  2018-04-10       Impact factor: 5.523

  1 in total

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