Literature DB >> 30002450

Failure of a T cell regulator: CD6 contributes to the aggravation of autoimmune inflammation.

Anja Meyer1, David M Kofler2.   

Abstract

Entities:  

Mesh：

Year:  2018        PMID： 30002450      PMCID： PMC6804726          DOI： 10.1038/s41423-018-0089-9

Source DB:  PubMed          Journal:  Cell Mol Immunol        ISSN： 1672-7681            Impact factor:   11.530


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  10 in total

1.  The CD6 multiple sclerosis susceptibility allele is associated with alterations in CD4+ T cell proliferation.

Authors:  David M Kofler; Christopher A Severson; Narine Mousissian; Philip L De Jager; David A Hafler
Journal:  J Immunol       Date:  2011-08-17       Impact factor: 5.422

2.  Dynamic coupling of ALCAM to the actin cortex strengthens cell adhesion to CD6.

Authors:  Joost Te Riet; Jonne Helenius; Nico Strohmeyer; Alessandra Cambi; Carl G Figdor; Daniel J Müller
Journal:  J Cell Sci       Date:  2014-02-04       Impact factor: 5.285

3.  Genetic and experimental evidence for the involvement of the CD6 lymphocyte receptor in psoriasis.

Authors:  Marta Consuegra-Fernández; Marc Julià; Mario Martínez-Florensa; Fernando Aranda; Cristina Català; Noelia Armiger-Borràs; María-Teresa Arias; Francisca Santiago; Antonio Guilabert; Anna Esteve; Carlos Muñoz; Carlos Ferrándiz; José-Manuel Carrascosa; Edurne Pedrosa; Jorge Romaní; Mercè Alsina; José-Manuel Mascaró-Galy; Francisco Lozano
Journal:  Cell Mol Immunol       Date:  2017-12-11       Impact factor: 11.530

4.  Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis.

Authors:  Verena Brucklacher-Waldert; Klarissa Stuerner; Manuela Kolster; Julia Wolthausen; Eva Tolosa
Journal:  Brain       Date:  2009-12       Impact factor: 13.501

5.  CD318 is a ligand for CD6.

Authors:  Gospel Enyindah-Asonye; Yan Li; Jeffrey H Ruth; Danislav S Spassov; Katie E Hebron; Andries Zijlstra; Mark M Moasser; Benlian Wang; Nora G Singer; Huadong Cui; Ray A Ohara; Stephanie M Rasmussen; David A Fox; Feng Lin
Journal:  Proc Natl Acad Sci U S A       Date:  2017-07-31       Impact factor: 11.205

6.  Efficacy and safety of itolizumab, a novel anti-CD6 monoclonal antibody, in patients with moderate to severe chronic plaque psoriasis: results of a double-blind, randomized, placebo-controlled, phase-III study.

Authors:  D S Krupashankar; Sunil Dogra; Mahendra Kura; Abir Saraswat; Leelavathy Budamakuntla; T K Sumathy; Radha Shah; M G Gopal; T Narayana Rao; C R Srinivas; Ramesh Bhat; Narendra Shetty; G Manmohan; Kotla Sai Krishna; Dalavoi Padmaja; Dasiga Venkata Subrahmanya Pratap; Vijay Garg; Sandesh Gupta; Neeraj Pandey; Uday Khopkar; Enrique Montero; M S Ramakrishnan; Pradip Nair; Prasanna C Ganapathi
Journal:  J Am Acad Dermatol       Date:  2014-04-02       Impact factor: 11.527

7.  The anti-CD6 antibody itolizumab provides clinical benefit without lymphopenia in rheumatoid arthritis patients: results from a 6-month, open-label Phase I clinical trial.

Authors:  P C Rodríguez; D M Prada; E Moreno; L E Aira; C Molinero; A M López; J A Gómez; I M Hernández; J P Martínez; Y Reyes; J M Milera; M V Hernández; R Torres; Y Avila; Y Barrese; C Viada; E Montero; P Hernández
Journal:  Clin Exp Immunol       Date:  2017-11-16       Impact factor: 4.330

8.  CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76.

Authors:  Namir J Hassan; Stephen J Simmonds; Nicholas G Clarkson; Sarah Hanrahan; Michael J Puklavec; Martine Bomb; A Neil Barclay; Marion H Brown
Journal:  Mol Cell Biol       Date:  2006-09       Impact factor: 4.272

9.  Multiple sclerosis susceptibility genes: associations with relapse severity and recovery.

Authors:  Ellen M Mowry; Robert F Carey; Maria R Blasco; Jean Pelletier; Pierre Duquette; Pablo Villoslada; Irina Malikova; Elaine Roger; R Phillip Kinkel; Jamie McDonald; Peter Bacchetti; Emmanuelle Waubant
Journal:  PLoS One       Date:  2013-10-09       Impact factor: 3.240

10.  CD6 modulates thymocyte selection and peripheral T cell homeostasis.

Authors:  Marc Orta-Mascaró; Marta Consuegra-Fernández; Esther Carreras; Romain Roncagalli; Amado Carreras-Sureda; Pilar Alvarez; Laura Girard; Inês Simões; Mario Martínez-Florensa; Fernando Aranda; Ramón Merino; Vanesa-Gabriela Martínez; Rubén Vicente; Jesús Merino; Adelaida Sarukhan; Marie Malissen; Bernard Malissen; Francisco Lozano
Journal:  J Exp Med       Date:  2016-07-04       Impact factor: 14.307
  10 in total
  2 in total

Review 1.  Migration and homeostasis of regulatory T cells in rheumatoid arthritis.

Authors:  Konstantin Kotschenreuther; Shuaifeng Yan; David M Kofler
Journal:  Front Immunol       Date:  2022-08-09       Impact factor: 8.786

Review 2.  Regulatory T cells in rheumatoid arthritis: functions, development, regulation, and therapeutic potential.

Authors:  Shuaifeng Yan; Konstantin Kotschenreuther; Shuya Deng; David M Kofler
Journal:  Cell Mol Life Sci       Date:  2022-09-29       Impact factor: 9.207
  2 in total

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