Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Sink into the Epigenome: Histones as Repositories That Influence Cellular Metabolism.

Literature DB >> 30001904

Sink into the Epigenome: Histones as Repositories That Influence Cellular Metabolism.

Abstract

Epigenetic modifications on chromatin are most commonly thought to be involved in the transcriptional regulation of gene expression. Due to their dependency on small-molecule metabolites, these modifications can relay information about cellular metabolic state to the genome for the activation or repression of particular sets of genes. In this review we discuss emerging evidence that these modifications might also have a metabolic purpose. Due to their abundance, the histones have the capacity to store substantial amounts of useful metabolites or to enable important metabolic transformations. Such metabolic functions for histones could help to explain the widespread occurrence of particular modifications that may not always be strongly correlated with transcriptional activity.

Entities: Chemical Disease Gene Species

Keywords: SAM; acetate; acetyl-CoA; epigenetics; histone acetylation; histone methylation

Mesh：

Substances：

Year: 2018 PMID： 30001904 PMCID： PMC6109460 DOI： 10.1016/j.tem.2018.06.002

Source DB: PubMed Journal: Trends Endocrinol Metab ISSN： 1043-2760 Impact factor: 12.015

81 in total

1. Catalytic mechanism of a MYST family histone acetyltransferase.

Authors: Christopher E Berndsen; Brittany N Albaugh; Song Tan; John M Denu
Journal: Biochemistry Date: 2007-01-23 Impact factor: 3.162

Review 2. On acetyl-CoA as a gauge of cellular metabolic state.

Authors: L Cai; B P Tu
Journal: Cold Spring Harb Symp Quant Biol Date: 2011-09-06

Review 3. Spatiotemporal Control of Acetyl-CoA Metabolism in Chromatin Regulation.

Authors: Sharanya Sivanand; Isabella Viney; Kathryn E Wellen
Journal: Trends Biochem Sci Date: 2017-11-23 Impact factor: 13.807

4. Nonenzymatic acetylation of histones with acetyl-CoA.

Authors: W K Paik; D Pearson; H W Lee; S Kim
Journal: Biochim Biophys Acta Date: 1970-08-08

5. A glycine N-methyltransferase knockout mouse model for humans with deficiency of this enzyme.

Authors: Zigmund Luka; Antonieta Capdevila; José M Mato; C Wagner
Journal: Transgenic Res Date: 2006-06 Impact factor: 2.788

Review 6. Metabolism of sulfur amino acids in Saccharomyces cerevisiae.

Authors: D Thomas; Y Surdin-Kerjan
Journal: Microbiol Mol Biol Rev Date: 1997-12 Impact factor: 11.056

7. Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy.

Authors: Xinjian Li; Willie Yu; Xu Qian; Yan Xia; Yanhua Zheng; Jong-Ho Lee; Wei Li; Jianxin Lyu; Ganesh Rao; Xiaochun Zhang; Chao-Nan Qian; Steven G Rozen; Tao Jiang; Zhimin Lu
Journal: Mol Cell Date: 2017-05-25 Impact factor: 17.970

8. Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation.

Authors: Joyce V Lee; Alessandro Carrer; Supriya Shah; Nathaniel W Snyder; Shuanzeng Wei; Sriram Venneti; Andrew J Worth; Zuo-Fei Yuan; Hee-Woong Lim; Shichong Liu; Ellen Jackson; Nicole M Aiello; Naomi B Haas; Timothy R Rebbeck; Alexander Judkins; Kyoung-Jae Won; Lewis A Chodosh; Benjamin A Garcia; Ben Z Stanger; Michael D Feldman; Ian A Blair; Kathryn E Wellen
Journal: Cell Metab Date: 2014-07-03 Impact factor: 27.287

9. A histone H3K36 chromatin switch coordinates DNA double-strand break repair pathway choice.

Authors: Chen-Chun Pai; Rachel S Deegan; Lakxmi Subramanian; Csenge Gal; Sovan Sarkar; Elizabeth J Blaikley; Carol Walker; Lydia Hulme; Eric Bernhard; Sandra Codlin; Jürg Bähler; Robin Allshire; Simon Whitehall; Timothy C Humphrey
Journal: Nat Commun Date: 2014-06-09 Impact factor: 14.919

Review 10. Acetyl-CoA and the regulation of metabolism: mechanisms and consequences.

Authors: Lei Shi; Benjamin P Tu
Journal: Curr Opin Cell Biol Date: 2015-02-20 Impact factor: 8.382

32 in total

1. A complex interplay between SAM synthetase and the epigenetic regulator SIN3 controls metabolism and transcription.

Authors: Mengying Liu; Nirmalya Saha; Ambikai Gajan; Nadia Saadat; Smiti V Gupta; Lori A Pile
Journal: J Biol Chem Date: 2019-11-27 Impact factor: 5.157

Review 2. Nuclear metabolism and the regulation of the epigenome.

Authors: Ruben Boon; Giorgia G Silveira; Raul Mostoslavsky
Journal: Nat Metab Date: 2020-10-12

Review 3. Metabolic choreography of gene expression: nutrient transactions with the epigenome.

Authors: Babukrishna Maniyadath; U S Sandra; Ullas Kolthur-Seetharam
Journal: J Biosci Date: 2020 Impact factor: 1.826

4. Demethylation of the Protein Phosphatase PP2A Promotes Demethylation of Histones to Enable Their Function as a Methyl Group Sink.

Authors: Cunqi Ye; Benjamin M Sutter; Yun Wang; Zheng Kuang; Xiaozheng Zhao; Yonghao Yu; Benjamin P Tu
Journal: Mol Cell Date: 2019-02-13 Impact factor: 17.970

Review 5. Acetate Metabolism in Physiology, Cancer, and Beyond.

Authors: Shree Bose; Vijyendra Ramesh; Jason W Locasale
Journal: Trends Cell Biol Date: 2019-05-31 Impact factor: 20.808

6. Glucose starvation induces a switch in the histone acetylome for activation of gluconeogenic and fat metabolism genes.

Authors: Wen-Chuan Hsieh; Benjamin M Sutter; Holly Ruess; Spencer D Barnes; Venkat S Malladi; Benjamin P Tu
Journal: Mol Cell Date: 2022-01-06 Impact factor: 17.970

Review 7. Metabolic regulation of epigenetic remodeling in immune cells.

Authors: Emily C Britt; Steven V John; Jason W Locasale; Jing Fan
Journal: Curr Opin Biotechnol Date: 2020-01-15 Impact factor: 9.740

8. ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism.

Authors: Zhiguang Huang; Menglu Zhang; Abigail A Plec; Sandi Jo Estill; Ling Cai; Joyce J Repa; Steven L McKnight; Benjamin P Tu
Journal: Proc Natl Acad Sci U S A Date: 2018-09-18 Impact factor: 11.205

Review 9. Metabolic and epigenetic regulation of T-cell exhaustion.

Authors: Fabien Franco; Alison Jaccard; Pedro Romero; Yi-Ru Yu; Ping-Chih Ho
Journal: Nat Metab Date: 2020-09-21

10. Alcohol metabolite acetic acid activates BK channels in a pH-dependent manner and decreases calcium oscillations and exocytosis of secretory granules in rat pituitary GH3 cells.

Authors: Ilnar Shaidullov; Elizaveta Ermakova; Aisylu Gaifullina; Anna Mosshammer; Aleksey Yakovlev; Thomas M Weiger; Anton Hermann; Guzel Sitdikova
Journal: Pflugers Arch Date: 2020-10-28 Impact factor: 3.657