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Literature DB >> 30001821

The role of Kupffer cells in hepatic iron and lipid metabolism.

Charlotte L Scott¹, Martin Guilliams².

Abstract

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Iron

Year: 2018 PMID： 30001821 PMCID： PMC7611037 DOI： 10.1016/j.jhep.2018.02.013

Source DB: PubMed Journal: J Hepatol ISSN： 0168-8278 Impact factor: 25.083

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11 in total

Review 1. Tissue biology perspective on macrophages.

Authors: Yasutaka Okabe; Ruslan Medzhitov
Journal: Nat Immunol Date: 2016-01 Impact factor: 25.606

Review 2. Dysregulation of iron and copper homeostasis in nonalcoholic fatty liver.

Authors: Elmar Aigner; Günter Weiss; Christian Datz
Journal: World J Hepatol Date: 2015-02-27

Review 3. Liver macrophages in tissue homeostasis and disease.

Authors: Oliver Krenkel; Frank Tacke
Journal: Nat Rev Immunol Date: 2017-03-20 Impact factor: 53.106

4. Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis.

Authors: Anne Leroux; Gladys Ferrere; Vanessa Godie; Frédéric Cailleux; Marie-Laure Renoud; Françoise Gaudin; Sylvie Naveau; Sophie Prévot; Samira Makhzami; Gabriel Perlemuter; Anne-Marie Cassard-Doulcier
Journal: J Hepatol Date: 2012-03-14 Impact factor: 25.083

5. Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-β.

Authors: Kevin M Hart; Thomas Fabre; Joshua C Sciurba; Richard L Gieseck; Lee A Borthwick; Kevin M Vannella; Thomas H Acciani; Rafael de Queiroz Prado; Robert W Thompson; Sandra White; Genevieve Soucy; Marc Bilodeau; Thirumalai R Ramalingam; Joseph R Arron; Naglaa H Shoukry; Thomas A Wynn
Journal: Sci Transl Med Date: 2017-06-28 Impact factor: 17.956

6. RORα Induces KLF4-Mediated M2 Polarization in the Liver Macrophages that Protect against Nonalcoholic Steatohepatitis.

Authors: Yong-Hyun Han; Hyeon-Ji Kim; Hyelin Na; Min-Woo Nam; Ju-Yeon Kim; Jun-Seok Kim; Seung-Hoi Koo; Mi-Ock Lee
Journal: Cell Rep Date: 2017-07-05 Impact factor: 9.423

Review 7. Abandoning M1/M2 for a Network Model of Macrophage Function.

Authors: Matthias Nahrendorf; Filip K Swirski
Journal: Circ Res Date: 2016-07-22 Impact factor: 17.367

Review 8. "Pumping iron"-how macrophages handle iron at the systemic, microenvironmental, and cellular levels.

Authors: Manfred Nairz; Igor Theurl; Filip K Swirski; Guenter Weiss
Journal: Pflugers Arch Date: 2017-03-01 Impact factor: 3.657

9. Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells.

Authors: Charlotte L Scott; Fang Zheng; Patrick De Baetselier; Liesbet Martens; Yvan Saeys; Sofie De Prijck; Saskia Lippens; Chloé Abels; Steve Schoonooghe; Geert Raes; Nick Devoogdt; Bart N Lambrecht; Alain Beschin; Martin Guilliams
Journal: Nat Commun Date: 2016-01-27 Impact factor: 14.919

10. On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver.

Authors: Igor Theurl; Ingo Hilgendorf; Manfred Nairz; Piotr Tymoszuk; David Haschka; Malte Asshoff; Shun He; Louisa M S Gerhardt; Tobias A W Holderried; Markus Seifert; Sieghart Sopper; Ashley M Fenn; Atsushi Anzai; Sara Rattik; Cameron McAlpine; Milan Theurl; Peter Wieghofer; Yoshiko Iwamoto; Georg F Weber; Nina K Harder; Benjamin G Chousterman; Tara L Arvedson; Mary McKee; Fudi Wang; Oliver M D Lutz; Emanuele Rezoagli; Jodie L Babitt; Lorenzo Berra; Marco Prinz; Matthias Nahrendorf; Guenter Weiss; Ralph Weissleder; Herbert Y Lin; Filip K Swirski
Journal: Nat Med Date: 2016-07-18 Impact factor: 53.440

22 in total

Review 1. The liver fibrosis niche: Novel insights into the interplay between fibrosis-composing mesenchymal cells, immune cells, endothelial cells, and extracellular matrix.

Authors: Michitaka Matsuda; Ekihiro Seki
Journal: Food Chem Toxicol Date: 2020-07-05 Impact factor: 6.023

2. COMMD10 is critical for Kupffer cell survival and controls Ly6C^hi monocyte differentiation and inflammation in the injured liver.

Authors: Keren Cohen; Odelia Mouhadeb; Shani Ben Shlomo; Marva Langer; Anat Neumann; Noam Erez; Itay Moshkovits; Rotem Pelet; Daniel J Kedar; Eli Brazowski; Martin Guilliams; Helen S Goodridge; Nathan Gluck; Chen Varol
Journal: Cell Rep Date: 2021-11-16 Impact factor: 9.423

The role of Kupffer cells in hepatic iron and lipid metabolism.

Review 1. Tissue biology perspective on macrophages.

Review 2. Dysregulation of iron and copper homeostasis in nonalcoholic fatty liver.

Review 3. Liver macrophages in tissue homeostasis and disease.

4. Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis.

5. Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-β.

6. RORα Induces KLF4-Mediated M2 Polarization in the Liver Macrophages that Protect against Nonalcoholic Steatohepatitis.

Review 7. Abandoning M1/M2 for a Network Model of Macrophage Function.

Review 8. "Pumping iron"-how macrophages handle iron at the systemic, microenvironmental, and cellular levels.

9. Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells.

10. On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver.

Review 1. The liver fibrosis niche: Novel insights into the interplay between fibrosis-composing mesenchymal cells, immune cells, endothelial cells, and extracellular matrix.

2. COMMD10 is critical for Kupffer cell survival and controls Ly6C^hi monocyte differentiation and inflammation in the injured liver.

3. Hepatic Stellate Cell-Macrophage Crosstalk in Liver Fibrosis and Carcinogenesis.

Review 4. Hepatic macrophages in liver homeostasis and diseases-diversity, plasticity and therapeutic opportunities.

5. IL-1 beta-mediated macrophage-hepatocyte crosstalk upregulates hepcidin under physiological low oxygen levels.

6. Atorvastatin Induces Hepatotoxicity in Diabetic Rats via Oxidative Stress, Inflammation, and Anti-Apoptotic Pathway.

Review 7. Single-cell technologies in hepatology: new insights into liver biology and disease pathogenesis.

8. Role of Tim4 in the regulation of ABCA1⁺ adipose tissue macrophages and post-prandial cholesterol levels.

9. Melatonin Effects on Non-Alcoholic Fatty Liver Disease Are Related to MicroRNA-34a-5p/Sirt1 Axis and Autophagy.

Review 10. Macrophages in obesity and non-alcoholic fatty liver disease: Crosstalk with metabolism.