Sikandar H Khan1, Michelle Kitsis2, Dmitriy Golovyan3, Sophia Wang4, Linda L Chlan5, Malaz Boustani6, Babar A Khan7. 1. Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Indiana University School of Medicine, Indianapolis, IN. Electronic address: sikhan@iu.edu. 2. Department of Medicine, Indiana University School of Medicine, Indianapolis, IN. 3. Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Indiana University School of Medicine, Indianapolis, IN. 4. Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN. 5. Department of Nursing, Nursing Research Division, Mayo Clinic, Rochester, MN. 6. Indiana University Center of Health Innovation and Implementation Science, Indianapolis, IN; IU Center of Aging Research, Regenstrief Institute, Indianapolis, IN; Sandra Eskenazi Center for Brain Care Innovation, Eskenazi Hospital, Indianapolis, IN; Division of Geriatrics and General Internal Medicine, Department of Internal Medicine, Indiana University School of Medicine, Indianapolis, IN; Indiana Clinical and Translational Research Institute, Indiana University School of Medicine, Indianapolis, Indiana. 7. Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Indiana University School of Medicine, Indianapolis, IN; Indiana University Center of Health Innovation and Implementation Science, Indianapolis, IN; Indiana Clinical and Translational Research Institute, Indiana University School of Medicine, Indianapolis, Indiana.
Abstract
BACKGROUND: Music listening has been shown to reduce anxiety, stress, and patient tolerance of procedures. Music may also have beneficial effects on inflammatory biomarkers in intensive care and post-operative patients, but the quality of evidence is not clear. OBJECTIVES: We conducted a systematic review to evaluate the effects of music on inflammatory biomarkers in intensive care, and post-operative patients. METHODS: A comprehensive search of the literature was performed. After screening 1570 references, full text review of 26 studies was performed. Fourteen studies were selected for inclusion. RESULTS: Seven studies showed a significant decrease in cortisol levels, but the level of evidence was low. Three studies had low risk of methodological bias, while 11 studies had high risk of bias. CONCLUSIONS: Music intervention may decrease cortisol levels, but other biomarkers remain unchanged. Given the low level of evidence, further research on music effects on inflammatory biomarkers is needed.
BACKGROUND: Music listening has been shown to reduce anxiety, stress, and patient tolerance of procedures. Music may also have beneficial effects on inflammatory biomarkers in intensive care and post-operative patients, but the quality of evidence is not clear. OBJECTIVES: We conducted a systematic review to evaluate the effects of music on inflammatory biomarkers in intensive care, and post-operative patients. METHODS: A comprehensive search of the literature was performed. After screening 1570 references, full text review of 26 studies was performed. Fourteen studies were selected for inclusion. RESULTS: Seven studies showed a significant decrease in cortisol levels, but the level of evidence was low. Three studies had low risk of methodological bias, while 11 studies had high risk of bias. CONCLUSIONS: Music intervention may decrease cortisol levels, but other biomarkers remain unchanged. Given the low level of evidence, further research on music effects on inflammatory biomarkers is needed.
Authors: Sikandar H Khan; Chenjia Xu; Russell Purpura; Sana Durrani; Heidi Lindroth; Sophia Wang; Sujuan Gao; Annie Heiderscheit; Linda Chlan; Malaz Boustani; Babar A Khan Journal: Am J Crit Care Date: 2020-03-01 Impact factor: 2.228
Authors: Usha Pant; Michael Frishkopf; Tanya Park; Colleen M Norris; Elizabeth Papathanassoglou Journal: Int J Environ Res Public Health Date: 2022-03-06 Impact factor: 3.390