Literature DB >> 30001634

Two new tetracyclic triterpenoids from the endophytic fungus Hypoxylon sp. 6269.

Han-Qiao Liang1,2, Da-Wei Zhang1,3, Shun-Xing Guo1, Jie Yu2.   

Abstract

Two new tetracyclic triterpenoids, integracide E (1) and isointegracide E (2), as well as three known secondary metabolites (i.e. integracide A (3), 2-deoxyintegracide A (4) and 2-deoxyintegracide B (5)), were isolated from mycelium of the endophytic fungus Hypoxylon sp. 6269. Structures were determined by a combination of 1D and 2D NMR techniques and mass spectrometry. All of the compounds were tested for their anti-HIV-1 integrase activities.

Entities:  

Keywords:  sp; Endophytic fungus; HIV-1 integrase; tetracyclic triterpenoids

Mesh:

Substances:

Year:  2018        PMID: 30001634     DOI: 10.1080/10286020.2018.1485662

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  2 in total

Review 1.  Endophytic Fungi: An Effective Alternative Source of Plant-Derived Bioactive Compounds for Pharmacological Studies.

Authors:  Juan Wen; Samuel Kumi Okyere; Shu Wang; Jianchen Wang; Lei Xie; Yinan Ran; Yanchun Hu
Journal:  J Fungi (Basel)       Date:  2022-02-20

2.  OSMAC Strategy Integrated with Molecular Networking for Accessing Griseofulvin Derivatives from Endophytic Fungi of Moquiniastrum polymorphum (Asteraceae).

Authors:  Victor F Farinella; Eunizinis S Kawafune; Marcelo M P Tangerina; Helori V Domingos; Leticia V Costa-Lotufo; Marcelo J P Ferreira
Journal:  Molecules       Date:  2021-12-02       Impact factor: 4.411

  2 in total

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