Literature DB >> 3000074

Association of the pX gene product of human T-cell leukemia virus type-I with nucleus.

T Kiyokawa, T Kawaguchi, M Seiki, M Yoshida.   

Abstract

Human T-cell leukemia virus type I (HTLV-I) contains a unique gene pX coding for p40 chi, and this protein was suggested to activate the transcription from the LTR of HTLV. By a similar mechanism, this viral function might be involved in immortalization of T-cells and leukemogenesis in adult T-cell leukemia induced by HTLV-I. In this communication, a part of the p40 chi was found to be tightly associated with nuclei in infected cell lines by subcellular fractionation and immunofluorescence staining.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 3000074     DOI： 10.1016/0042-6822(85)90149-7

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  15 in total

1.  Interaction of Gli2 with CREB protein on DNA elements in the long terminal repeat of human T-cell leukemia virus type 1 is responsible for transcriptional activation by tax protein.

Authors:  S Dan; A Tanimura; M Yoshida
Journal:  J Virol       Date:  1999-04       Impact factor: 5.103

2.  Complex formation of human T-cell leukemia virus type I p40tax transactivator with cellular polypeptides.

Authors:  K Nagata; Y Ide; T Takagi; K Ohtani; M Aoshima; H Tozawa; M Nakamura; K Sugamura
Journal:  J Virol       Date:  1992-02       Impact factor: 5.103

3.  Indirect binding of human T-cell leukemia virus type I tax1 to a responsive element in the viral long terminal repeat.

Authors:  S J Marriott; I Boros; J F Duvall; J N Brady
Journal:  Mol Cell Biol       Date:  1989-10       Impact factor: 4.272

4.  Abundant synthesis of functional human T-cell leukemia virus type I p40x protein in eucaryotic cells by using a baculovirus expression vector.

Authors:  K T Jeang; C Z Giam; M Nerenberg; G Khoury
Journal:  J Virol       Date:  1987-03       Impact factor: 5.103

5.  The human T-cell leukemia virus type 1 transactivator protein Tax colocalizes in unique nuclear structures with NF-kappaB proteins.

Authors:  F Bex; A McDowall; A Burny; R Gaynor
Journal:  J Virol       Date:  1997-05       Impact factor: 5.103

6.  Tax protein of human T-cell leukemia virus type I binds to the ankyrin motifs of inhibitory factor kappa B and induces nuclear translocation of transcription factor NF-kappa B proteins for transcriptional activation.

Authors:  H Hirai; T Suzuki; J Fujisawa; J Inoue; M Yoshida
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-26       Impact factor: 11.205

7.  Kinetic analysis of human T-cell leukemia virus type I Tax-mediated activation of NF-kappa B.

Authors:  T Kanno; K Brown; G Franzoso; U Siebenlist
Journal:  Mol Cell Biol       Date:  1994-10       Impact factor: 4.272

8.  Expression and characterization of the trans-activating protein Tax of human T-cell leukemia virus type I in Saccharomyces cerevisiae.

Authors:  L C Wu; T H Tan; S I Shahied
Journal:  J Virol       Date:  1992-12       Impact factor: 5.103

9.  A cis element required for induction of the interleukin 2 enhancer by human T-cell leukemia virus type I binds a novel Tax-inducible nuclear protein.

Authors:  M Li; M Siekevitz
Journal:  Mol Cell Biol       Date:  1993-10       Impact factor: 4.272

10.  The trans-activator tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1.

Authors:  T Suzuki; J I Fujisawa; M Toita; M Yoshida
Journal:  Proc Natl Acad Sci U S A       Date:  1993-01-15       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.