The Role of Continuous Cerebrospinal Fluid Pulsation Stress in the Remodeling of Artificial Vertebral Laminae: A Comparison Experiment.

IMPACT STATEMENT: In this study, we designed a comparison study to investigate the effect of continuous cerebrospinal fluid pulsation (CSFP) stress on the remodeling of artificial vertebral laminae, and we found that the continuous CSFP stress played an important role in the physiological reconstruction of artificial vertebral laminae by promoting the remodeling abilities of tissue-engineered laminae (TEL). It deepens our understanding of the in vivo development of TEL, and the impact of biomechanical stimuli on the osteogenesis and remodeling.