| Literature DB >> 29998521 |
Magdalena Wąsik1, Katarzyna Nazimek1, Krzysztof Bryniarski1.
Abstract
A diverse population of regulatory B (Breg) cells reportedly exhibits significant immunomodulatory effects in various models of inflammatory responses and infectious diseases caused by bacteria, viruses or parasites. Breg cells contribute to maintenance of homeostasis via IL-10 production and multiple IL-10-independent mechanisms. The current review describes various phenotypic and functional subsets of Breg cells in autoimmune and infectious diseases and discusses the impacts of experimental conditions that have been found to drive Breg cell differentiation.Entities:
Keywords: Breg cell; autoimmune diseases; immunoregulation; infectious diseases
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Year: 2018 PMID: 29998521 DOI: 10.1111/1348-0421.12636
Source DB: PubMed Journal: Microbiol Immunol ISSN: 0385-5600 Impact factor: 1.955