Literature DB >> 29997692

Aspirin versus placebo in pregnancies at high risk for preterm pre-eclampsia.

Lisa Story1, Catherine Nelson-Piercy1.   

Abstract

A recent multicentre placebo-controlled trial by Rolnick et al. has indicated that taking 150 mg aspirin daily in women at high risk of pre-eclampsia reduced the incidence of the disease from 4.3% to 1.5% in comparison with placebo. Although the findings of this study are important, a high proportion of women withdrew their consent and not all safety outcomes have been reported. This journal watch article discusses the paper in more detail.

Entities:  

Keywords:  Aspirin; pre-eclampsia

Year:  2018        PMID: 29997692      PMCID: PMC6038012          DOI: 10.1177/1753495X18775898

Source DB:  PubMed          Journal:  Obstet Med        ISSN: 1753-495X


  7 in total

1.  Prevention of preeclampsia and intrauterine growth restriction with aspirin started in early pregnancy: a meta-analysis.

Authors:  Emmanuel Bujold; Stéphanie Roberge; Yves Lacasse; Marc Bureau; François Audibert; Sylvie Marcoux; Jean-Claude Forest; Yves Giguère
Journal:  Obstet Gynecol       Date:  2010-08       Impact factor: 7.661

2.  Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy.

Authors: 
Journal:  Obstet Gynecol       Date:  2013-11       Impact factor: 7.661

3.  Aspirin for Evidence-Based Preeclampsia Prevention trial: effect of aspirin in prevention of preterm preeclampsia in subgroups of women according to their characteristics and medical and obstetrical history.

Authors:  Liona C Poon; David Wright; Daniel L Rolnik; Argyro Syngelaki; Juan Luis Delgado; Theodora Tsokaki; Gergo Leipold; Ranjit Akolekar; Siobhan Shearing; Luciana De Stefani; Jacques C Jani; Walter Plasencia; Nikolaos Evangelinakis; Otilia Gonzalez-Vanegas; Nicola Persico; Kypros H Nicolaides
Journal:  Am J Obstet Gynecol       Date:  2017-08-04       Impact factor: 8.661

Review 4.  The role of aspirin dose on the prevention of preeclampsia and fetal growth restriction: systematic review and meta-analysis.

Authors:  Stéphanie Roberge; Kypros Nicolaides; Suzanne Demers; Jon Hyett; Nils Chaillet; Emmanuel Bujold
Journal:  Am J Obstet Gynecol       Date:  2016-09-15       Impact factor: 8.661

5.  Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia.

Authors:  Daniel L Rolnik; David Wright; Liona C Poon; Neil O'Gorman; Argyro Syngelaki; Catalina de Paco Matallana; Ranjit Akolekar; Simona Cicero; Deepa Janga; Mandeep Singh; Francisca S Molina; Nicola Persico; Jacques C Jani; Walter Plasencia; George Papaioannou; Kinneret Tenenbaum-Gavish; Hamutal Meiri; Sveinbjorn Gizurarson; Kate Maclagan; Kypros H Nicolaides
Journal:  N Engl J Med       Date:  2017-06-28       Impact factor: 91.245

6.  Prevention of perinatal death and adverse perinatal outcome using low-dose aspirin: a meta-analysis.

Authors:  S Roberge; K H Nicolaides; S Demers; P Villa; E Bujold
Journal:  Ultrasound Obstet Gynecol       Date:  2013-05       Impact factor: 7.299

Review 7.  Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data.

Authors:  Lisa M Askie; Lelia Duley; David J Henderson-Smart; Lesley A Stewart
Journal:  Lancet       Date:  2007-05-26       Impact factor: 79.321

  7 in total

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