Zou-Qin Huang1, Tao Li. 1. Affiliated Cancer Hospital of Guangzhou Medical University, Guangzhou 510095, China. E-mail: huangzouqin@126.com.
Abstract
OBJECTIVE: To assess the clinical value of left ventricular Tei-index in early evaluation of cardiac function in hypertensive patients with left ventricular hypertrophy after radiochemotherapy. METHODS: Thirty hypertensive patients with malignancies and left ventricular hypertrophy and 30 hypertensive patients with malignancies without left ventricular hypertrophy were enrolled in this study, with 30 normotensive patients with malignancies as the control group. Left ventricular Tei-index and cardiac function indexes of the patients were detected using Doppler echocardiography before and after radiochemotherapy, and the changes in the cardiac function index and left ventricular Tei-index were compared among the 3 groups. RESULTS: After radiochemotherapy, left ventricular Tei-index was significantly higher in hypertensive patients with left ventricular hypertrophy than in the control patients and hypertensive patients without left ventricular hypertrophy (P<0.05), and was similar between the latter two groups. No significant differences were found in the changes of left ventricular ejection fraction (EF), ratio of the early to late ventricular filling velocities (E/A ratio), or end-systolic volume (EDV) among the 3 groups after radiochemotherapy. CONCLUSION: Tei-index is more sensitive than traditional echocardiography in assessing the changes of cardiac functions in hypertensive patients with left ventricular hypertrophy after chemotherapy.
OBJECTIVE: To assess the clinical value of left ventricular Tei-index in early evaluation of cardiac function in hypertensivepatients with left ventricular hypertrophy after radiochemotherapy. METHODS: Thirty hypertensivepatients with malignancies and left ventricular hypertrophy and 30 hypertensivepatients with malignancies without left ventricular hypertrophy were enrolled in this study, with 30 normotensive patients with malignancies as the control group. Left ventricular Tei-index and cardiac function indexes of the patients were detected using Doppler echocardiography before and after radiochemotherapy, and the changes in the cardiac function index and left ventricular Tei-index were compared among the 3 groups. RESULTS: After radiochemotherapy, left ventricular Tei-index was significantly higher in hypertensivepatients with left ventricular hypertrophy than in the control patients and hypertensivepatients without left ventricular hypertrophy (P<0.05), and was similar between the latter two groups. No significant differences were found in the changes of left ventricular ejection fraction (EF), ratio of the early to late ventricular filling velocities (E/A ratio), or end-systolic volume (EDV) among the 3 groups after radiochemotherapy. CONCLUSION: Tei-index is more sensitive than traditional echocardiography in assessing the changes of cardiac functions in hypertensivepatients with left ventricular hypertrophy after chemotherapy.
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