Literature DB >> 299957

Ribavirin: efficacy in the treatment of murine autoimmune disease.

L W Klassen, D R Budman, G W Williams, A D Steinberg, N L Gerber.   

Abstract

Ribavirin, a drug with known antiviral activity, was given to mice with established lupus nephritis. Ribavirin was effective in prolonging survival, reducing the titer of antibodies to DNA, and reversing proteinuria. Other antiviral agents were not effective in the dosages used.

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Year:  1977        PMID: 299957     DOI: 10.1126/science.299957

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  12 in total

1.  Therapeutic effect of beta-[1-phenyl-5-bis(beta-chloroethyl)-amino-benzimidazolyl-(2)-DL-alanin (ZIMET 3164) on immune complex nephritis of NZB hybrid mice.

Authors:  J Güttner
Journal:  Agents Actions       Date:  1979-12

2.  Controversies' clarification regarding ribavirin efficacy in measles and coronaviruses: Comprehensive therapeutic approach strictly tailored to COVID-19 disease stages.

Authors:  George D Liatsos
Journal:  World J Clin Cases       Date:  2021-07-06       Impact factor: 1.337

3.  The effect of exogenous interferon: acceleration of autoimmune and renal diseases in (NZB/W) F1 mice.

Authors:  C Adam; Y Thoua; P Ronco; P Verroust; M Tovey; L Morel-Maroger
Journal:  Clin Exp Immunol       Date:  1980-05       Impact factor: 4.330

4.  Levamisole maintains cyclophsophamide-induced remission in murine lupus erythematosus.

Authors:  J Zulman; J Michalski; C McCombs; J Greenspan; N Talal
Journal:  Clin Exp Immunol       Date:  1978-02       Impact factor: 4.330

5.  Animal model of human disease. Angioimmunoblastic lymphadenopathy with dysproteinemia.

Authors:  T D Gindhart; J S Greenspan
Journal:  Am J Pathol       Date:  1980-06       Impact factor: 4.307

6.  Effects of ribavirin on BHK-21 cells acutely or persistently infected with mumps virus.

Authors:  J R McCammon; V W Riesser
Journal:  Antimicrob Agents Chemother       Date:  1979-03       Impact factor: 5.191

7.  Inhibition of lymphocyte proliferative responses by ribavirin.

Authors:  D L Peavy; W C Koff; D S Hyman; V Knight
Journal:  Infect Immun       Date:  1980-08       Impact factor: 3.441

8.  Selective inhibition of functional lymphocyte subpopulations by ribavirin.

Authors:  C N Powers; D L Peavy; V Knight
Journal:  Antimicrob Agents Chemother       Date:  1982-07       Impact factor: 5.191

9.  Treatment of (NZB x NZW)F1 disease with anti-I-A monoclonal antibodies.

Authors:  N E Adelman; D L Watling; H O McDevitt
Journal:  J Exp Med       Date:  1983-10-01       Impact factor: 14.307

Review 10.  Animal models of human systemic lupus erythematosus.

Authors:  D P Huston; A D Steinberg
Journal:  Yale J Biol Med       Date:  1979 May-Jun
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