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Literature DB >> 29995047

Redox-responsive cisplatin nanogels for anticancer drug delivery.

Abstract

Inspired by cisplatin's deactivation by glutathione (GSH) in cancer, a GSH responsive nanogel loaded with doxorubicin (Dox) was prepared using hyaluronan as a matrix and cisplatin as a crosslinker. The elevated GSH depletes the cisplatin crosslinker in the nanogel, enhances Dox release and boosts cytotoxicity, thus providing a new GSH responsive platform to reverse cisplatin resistance.

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Year: 2018 PMID： 29995047 PMCID： PMC6057802 DOI： 10.1039/c8cc01795f

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

29 in total

1. A molecular view of cisplatin's mode of action: interplay with DNA bases and acquired resistance.

Authors: M Paula M Marques; Diego Gianolio; Giannantonio Cibin; John Tomkinson; Stewart F Parker; Rosendo Valero; R Pedro Lopes; Luis A E Batista de Carvalho
Journal: Phys Chem Chem Phys Date: 2015-02-21 Impact factor: 3.676

2. Differences in cisplatin distribution in sensitive and resistant ovarian cancer cells: a TEM/NanoSIMS study.

Authors: Ronald F S Lee; Tina Riedel; Stéphane Escrig; Catherine Maclachlan; Graham W Knott; Curt A Davey; Kai Johnsson; Anders Meibom; Paul J Dyson
Journal: Metallomics Date: 2017-10-18 Impact factor: 4.526

3. Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels.

Authors: Periannan Kuppusamy; Haiquan Li; Govindasamy Ilangovan; Arturo J Cardounel; Jay L Zweier; Kenichi Yamada; Murali C Krishna; James B Mitchell
Journal: Cancer Res Date: 2002-01-01 Impact factor: 12.701

4. Cisplatin Cross-Linked Multifunctional Nanodrugplexes for Combination Therapy.

Authors: Weiqi Zhang; Ching-Hsuan Tung
Journal: ACS Appl Mater Interfaces Date: 2017-03-01 Impact factor: 9.229

5. Microenvironmental InterFereNce of metabolism regulates chemosensitivity.

Authors: Leila Akkari; Johanna A Joyce
Journal: Cell Res Date: 2016-06-28 Impact factor: 25.617

Review 6. Glutathione in cancer biology and therapy.

Authors: José M Estrela; Angel Ortega; Elena Obrador
Journal: Crit Rev Clin Lab Sci Date: 2006 Impact factor: 6.250

Review 7. Cisplatin resistance and opportunities for precision medicine.

Authors: Lauren Amable
Journal: Pharmacol Res Date: 2016-01-22 Impact factor: 7.658

Review 8. The resurgence of platinum-based cancer chemotherapy.

Authors: Lloyd Kelland
Journal: Nat Rev Cancer Date: 2007-07-12 Impact factor: 60.716

9. Spectrophotometric determination of platinum with o-phenylenediamine.

Authors: E D Golla; G H Ayres
Journal: Talanta Date: 1973-02 Impact factor: 6.057

10. Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death.

Authors: Emarndeena H Cheteh; Martin Augsten; Helene Rundqvist; Julie Bianchi; Victoria Sarne; Lars Egevad; Vladimir Jn Bykov; Arne Östman; Klas G Wiman
Journal: Cell Death Dis Date: 2017-06-01 Impact factor: 8.469

6 in total

1. Therapeutic polymeric nanomedicine: GSH-responsive release promotes drug release for cancer synergistic chemotherapy.

Authors: Jie Shen; Qiwen Wang; Jie Fang; Wangxing Shen; Dan Wu; Guping Tang; Jie Yang
Journal: RSC Adv Date: 2019-11-15 Impact factor: 4.036

2. Hypoxia-degradable and long-circulating zwitterionic phosphorylcholine-based nanogel for enhanced tumor drug delivery.

Authors: Shaojun Peng; Boshu Ouyang; Yongjie Xin; Wei Zhao; Shun Shen; Meixiao Zhan; Ligong Lu
Journal: Acta Pharm Sin B Date: 2020-08-26 Impact factor: 11.413