Literature DB >> 2999125

Structural elucidation of the disulfated oligosaccharide from bovine lutropin.

E D Green, H van Halbeek, I Boime, J U Baenziger.   

Abstract

The Asn-linked oligosaccharides of the pituitary hormone lutropin (LH) contain both sulfate and GalNAc. Bovine pituitary explants incorporate [3H]glucosamine, [3H]mannose, [3H]fucose, and [35S]sulfate into the Asn-linked oligosaccharides of LH. Endoglycosidase F or N-glycanase releases the [3H]glucosamine- and [3H]mannose-labeled oligosaccharides from the protein, which resolve on anion-exchange high pressure liquid chromatography as neutral (S-0), mono- (S-1), and disulfated (S-2) species. Based on sequential enzyme digestion, methylation, periodate oxidation, and nuclear magnetic resonance studies, the proposed structure for S-2 is as follows: formula see text. Sulfate is confined to position 3 or 4 of GalNAc based on periodate and methylation data and can be removed by methanolysis. The presence of beta-linked GalNAc at a position typically occupied by Gal has not previously been observed.

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Year:  1985        PMID： 2999125

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  25 in total

Review 1.  Molecular structures of glycoprotein hormones and functions of their carbohydrate components.

Authors:  A Stockell Hartree; A G Renwick
Journal:  Biochem J       Date:  1992-11-01       Impact factor: 3.857

2.  Peptide-specific transfer of N-acetylgalactosamine to O-linked glycans by the glycosyltransferases β1,4-N-acetylgalactosaminyl transferase 3 (β4GalNAc-T3) and β4GalNAc-T4.

Authors:  Dorothy Fiete; Mary Beranek; Jacques U Baenziger
Journal:  J Biol Chem       Date:  2012-06-21       Impact factor: 5.157

Review 3.  Carbohydrate analysis of glycoproteins. A review.

Authors:  K B Lee; D Loganathan; Z M Merchant; R J Linhardt
Journal:  Appl Biochem Biotechnol       Date:  1990-01       Impact factor: 2.926

4.  Regulation of lutropin circulatory half-life by the mannose/N-acetylgalactosamine-4-SO4 receptor is critical for implantation in vivo.

Authors:  Yiling Mi; Steven D Shapiro; Jacques U Baenziger
Journal:  J Clin Invest       Date:  2002-01       Impact factor: 14.808

5.  Functional Consequences of Mannose and Asialoglycoprotein Receptor Ablation.

Authors:  Yiling Mi; Marcy Coonce; Dorothy Fiete; Lindsay Steirer; Gabriela Dveksler; R Reid Townsend; Jacques U Baenziger
Journal:  J Biol Chem       Date:  2016-07-12       Impact factor: 5.157

6.  O-linked N,N'-diacetyllactosamine (LacdiNAc)-modified glycans in extracellular matrix glycoproteins are specifically phosphorylated at subterminal N-acetylglucosamine.

Authors:  Isabelle Breloy; Sandra Pacharra; Philipp Ottis; David Bonar; Ammi Grahn; Franz-Georg Hanisch
Journal:  J Biol Chem       Date:  2012-04-03       Impact factor: 5.157

7.  Identification of mammalian glycoproteins with type-I LacdiNAc structures synthesized by the glycosyltransferase B3GALNT2.

Authors:  Takahiro Nakane; Kiyohiko Angata; Takashi Sato; Hiroyuki Kaji; Hisashi Narimatsu
Journal:  J Biol Chem       Date:  2019-03-21       Impact factor: 5.157

8.  Modulation of mannose and asialoglycoprotein receptor expression determines glycoprotein hormone half-life at critical points in the reproductive cycle.

Authors:  Yiling Mi; Angela Lin; Dorothy Fiete; Lindsay Steirer; Jacques U Baenziger
Journal:  J Biol Chem       Date:  2014-03-11       Impact factor: 5.157

9.  An in-depth Comparison of the Pediatric and Adult Urinary N-glycomes.

Authors:  Haiying Li; Viral Patel; Shannon E DiMartino; John W Froehlich; Richard S Lee
Journal:  Mol Cell Proteomics       Date:  2020-07-31       Impact factor: 5.911

10.  Murine and human zona pellucida 3 derived from mouse eggs express identical O-glycans.

Authors:  Anne Dell; Sara Chalabi; Richard L Easton; Stuart M Haslam; Mark Sutton-Smith; Manish S Patankar; Frank Lattanzio; Maria Panico; Howard R Morris; Gary F Clark
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-12       Impact factor: 11.205
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