Bernd Saugel1, F Javier Belda2,3. 1. Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. 2. Department of Surgery, University of Valencia, Valencia, Spain - fco.javier.belda@uv.es. 3. Department of Anesthesiology and Critical Care, Hospital Clínico Universitario, Valencia, Spain.