Literature DB >> 29990039

Probabilistic Dimensionality Reduction via Structure Learning.

Li Wang, Qi Mao.   

Abstract

We propose an alternative probabilistic dimensionality reduction framework that can naturally integrate the generative model and the locality information of data. Based on this framework, we present a new model, which is able to learn a set of embedding points in a low-dimensional space by retaining the inherent structure from high-dimensional data. The objective function of this new model can be equivalently interpreted as two coupled learning problems, i.e., structure learning and the learning of projection matrix. Inspired by this interesting interpretation, we propose another model, which finds a set of embedding points that can directly form an explicit graph structure. We proved that the model by learning explicit graphs generalizes the reversed graph embedding method, but leads to a natural interpretation from Bayesian perspective. This can greatly facilitate data visualization and scientific discovery in downstream analysis. Extensive experiments are performed that demonstrate that the proposed framework is able to retain the inherent structure of datasets and achieve competitive quantitative results in terms of various performance evaluation criteria.

Year:  2017        PMID: 29990039     DOI: 10.1109/TPAMI.2017.2785402

Source DB:  PubMed          Journal:  IEEE Trans Pattern Anal Mach Intell        ISSN: 0098-5589            Impact factor:   6.226


  8 in total

1.  Immune Subtypes and Immune Landscape Analysis of Endometrial Carcinoma.

Authors:  Leilei Liang; Yunshu Zhu; Jian Li; Jia Zeng; Guangwen Yuan; Lingying Wu
Journal:  J Immunol       Date:  2022-09-12       Impact factor: 5.426

2.  Identification of glioblastoma immune subtypes and immune landscape based on a large cohort.

Authors:  Huiyuan Zhang; Ying Chen
Journal:  Hereditas       Date:  2021-08-19       Impact factor: 3.271

3.  Identification and Validation of Immune Molecular Subtypes and Immune Landscape Based on Colon Cancer Cohort.

Authors:  Wenqian Qi; Qian Zhang
Journal:  Front Med (Lausanne)       Date:  2022-05-06

4.  Identification and Validation of the Immune Subtypes of Lung Adenocarcinoma: Implications for Immunotherapy.

Authors:  Yang Song; Shi Yan; Weina Fan; Mengyan Zhang; Wei Liu; Hailing Lu; Mengru Cao; Chenguang Hao; Lin Chen; Fanglin Tian; Yuning Zhan; Li Cai; Ying Xing
Journal:  Front Cell Dev Biol       Date:  2020-07-03

5.  Robust and Scalable Learning of Complex Intrinsic Dataset Geometry via ElPiGraph.

Authors:  Luca Albergante; Evgeny Mirkes; Jonathan Bac; Huidong Chen; Alexis Martin; Louis Faure; Emmanuel Barillot; Luca Pinello; Alexander Gorban; Andrei Zinovyev
Journal:  Entropy (Basel)       Date:  2020-03-04       Impact factor: 2.524

6.  Single-cell transcriptome atlas of human mesenchymal stem cells exploring cellular heterogeneity.

Authors:  Zheng Wang; Chengyan Chai; Rui Wang; Yimei Feng; Lei Huang; Yiming Zhang; Xia Xiao; Shijie Yang; Yunfang Zhang; Xi Zhang
Journal:  Clin Transl Med       Date:  2021-12

7.  Identification of Tumor Antigens and Design of mRNA Vaccine for Colorectal Cancer Based on the Immune Subtype.

Authors:  Cong Liu; Dimitri Papukashvili; Yu Dong; Xingyun Wang; Xing Hu; Nuo Yang; Jie Cai; Fengfei Xie; Nino Rcheulishvili; Peng George Wang
Journal:  Front Cell Dev Biol       Date:  2022-01-20

8.  Immune signature-based hepatocellular carcinoma subtypes may provide novel insights into therapy and prognosis predictions.

Authors:  Qiuxian Zheng; Qin Yang; Jiaming Zhou; Xinyu Gu; Haibo Zhou; Xuejun Dong; Haihong Zhu; Zhi Chen
Journal:  Cancer Cell Int       Date:  2021-06-30       Impact factor: 5.722

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.